Results 41 to 50 of about 17,803,086 (271)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Parent-adolescent communication, self-esteem, and suicidal ideation in Chinese adolescents: evidence from a four-wave longitudinal study

Frontiers in Psychiatry
BackgroundPrevious studies have linked parent–adolescent communication and self-esteem to adolescent suicidal ideation; however, less is known about how these relationships unfold over time, whether maternal and paternal communication play different ...
Kun Hu, Bin Li
doaj   +1 more source

Determinants of economic growth regencies/cities in Jambi Province with dynamic panel data approach

Jurnal Perspektif Pembiayaan dan Pembangunan Daerah, 2022
This study aims to analyze the determinants of economic growth Regency/City in Jambi Province. The factors considered to be the determinants of economic growth are lagged economic growth, government expenditure, household consumption, labor, and ...
Hajri Puja Pratama, Syaparuddin Syaparuddin, Emilia Emilia   +2 more
doaj   +1 more source

Tutorial in Longitudinal Measurement Invariance and Cross-lagged Panel Models Using Lavaan

Meta-Psychology, 2020
In longitudinal studies involving multiple latent variables, researchers often seek to predict how iterations of latent variables measured at early time points predict iterations measured at later time points. Cross-lagged panel modeling, a form of structural equation modeling, is a useful way to conceptualize and test these relationships.
Sean Mackinnon, Robin Curtis, Roisin O'Connor   +2 more
openaire   +2 more sources

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Understanding the Effect of Loneliness on Quality of Life in Older Adults from Longitudinal Approaches

Psychosocial Intervention
Aim: To study the longitudinal relationship between loneliness and quality of life (QoL) in adults to identify key mechanisms to better design future psychosocial interventions.
Zaira Torres, Amparo Oliver, José M. Tomás   +2 more
doaj   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Longitudinal associations between memory and emergent literacy from 3 to 6 years of age: a four-wave random-intercept cross-lagged panel study

BMC Psychology
Background Memory and emergent literacy are foundational to children’s early learning. However, it remains unclear whether their longitudinal association reflects stable differences between children, developmental fluctuations within children, or both ...
Jin-long Liang, Xin-ling Cui
doaj   +1 more source

Environmental, social and governance aspects and financial performance: A symbiotic relationship in Indian manufacturing

Cleaner Production Letters
Studying Environmental, Social, and Governance (ESG) aspects and firm performance is crucial for globally understanding how sustainable practices drive long-term profitability and competitiveness in diverse markets.
Umakanta Gartia, Ajaya Kumar Panda, Apoorva Hegde, Swagatika Nanda   +3 more
doaj   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source