Results 61 to 70 of about 363,864 (306)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Cross-layer design and optimization for wireless sensor networks [PDF]

open access: yes, 2006
Cross-layer design and optimization is a new technique which can be used to design and improve the performance in both wireless and wireline networks.
Lim, Tat Lee
core  

Cross layer design of wireless LAN for telemedicine application

open access: yes, 2009
Telemedicine system requires an acceptable network quality of service and cost. IEEE 802.11 wireless LAN technology has been developed to provide scalable and low cost network.
Supriyanto, Eko   +3 more
core   +1 more source

Cross-Layer radio resource allocation: the journey so far and the road ahead [PDF]

open access: yes, 2009
The cross-layer concept originated almost ten years ago with the aim of taking the most advantage from the difficult wireless media to break the barriers imposed by the layered transmission.
Virginia Corvino   +14 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Cross-layer design in optical networks

open access: yes, 2013
Optical networks have become an integral part of the communications infrastructure needed to support society’s demand for high-speed connectivity.  Cross-Layer Design in Optical Networks addresses topics in optical network design and analysis with a ...
Subramaniam, Suresh   +6 more
core   +1 more source

Airborne Cognitive Networking: Design, Development, and Deployment

open access: yesIEEE Access, 2018
We design, develop, and experimentally validate a complete integrated software/hardware platform for airborne cognitive networking in both indoor and outdoor environments.
George Sklivanitis   +15 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Editorial of cross-layer design issues, challenges and opportunities for future intelligent heterogeneous networks

open access: yes, 2023
Editorial of cross-layer design issues, challenges and opportunities for future intelligent heterogeneous ...
B S Kim (13541428)   +4 more
core  

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