Results 111 to 120 of about 681,701 (308)
Background and Objective: In the last decade, cross-linking (CXL) has been widely used for treating people with progressive keratoconus. The present study aimed to compare corneal aberrometry parameters before and after CXL in patients with keratoconus ...
Mehdi Alizadeh +2 more
doaj
Ethynyl and substituted ethynyl-terminated polysulfones [PDF]
Ethynyl and substituted ethynyl-terminated polysulfones and their synthesis are disclosed. These polysulfones are thermally cured to induce cross-linking and chain extension, producing a polymer system with improved solvent resistance and use ...
Hergenrother, P. M.
core +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Effect of lignins on structure, tensile and thermal properties of polyurethanes films [PDF]
The organosolv lignins of wheat straw acts as a cross linking macromonomer in PU compositions. The fractionation of lignin and variation of fractions contents in PU composition allow to control the properties of PU films and to obtain the elastomers in ...
Arshanitsa, Alexandr +3 more
core
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Collagen cross-linking: Strengthening the unstable cornea
Oren Tomkins, Hanna J GarzoziDepartment of Ophthalmology, Bnai Zion Medical Center, Haifa, IsraelAbstract: Corneal ectasia, a weakening of corneal integrity, occurs both due to acquired and congenital conditions such as keratoconus.
Oren Tomkins, Hanna J Garzozi
doaj
Cross-Linking and Structure of Polymer Networks Intramolecular Reaction: Effects on Network Formation Selective Quenching of Large-Scale Molecular Motions Rubber Elasticity Modulus Star-Branched Nylon 6 Urethane and Melamine-Formaldehyde Coatings Effect of Ionizing Radiation on Epoxy Adhesive Frequency-Dependent Dielectric Analysis Fluorescence Optrode
openaire +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source

