Results 111 to 120 of about 4,936,875 (304)

L,D‑Transpeptidase Specific Probe Reveals Spatial Activity of Peptidoglycan Cross-Linking

, 2019
Peptidoglycan (PG) is a cross-linked, meshlike scaffold endowed with the strength to withstand the internal pressure of bacteria. Bacteria are known to heavily remodel their peptidoglycan stem peptides, yet little is known about the physiological impact ...
Marcos M. Pires (690294), Martin S. Pavelka (7388567), Moagi Shaku (7388558), Julia M. Nelson (7388555), M. Nurul Islam (7388564), Dean C. Crick (364125), Sean E. Pidgeon (1660543), Sung Joon Kim (190372), Binayak Rimal (7388561), Bavesh D. Kana (7388570), Alexis J. Apostolos (7388552)   +10 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Collagen cross-linking: Strengthening the unstable cornea

Clinical Ophthalmology, 2008
Oren Tomkins, Hanna J GarzoziDepartment of Ophthalmology, Bnai Zion Medical Center, Haifa, IsraelAbstract: Corneal ectasia, a weakening of corneal integrity, occurs both due to acquired and congenital conditions such as keratoconus.
Oren Tomkins, Hanna J Garzozi
doaj  

Cross-linking??? ?????? PI ???????????? ????????? ?????? ??????

, 2020
?????? ??????????????? PI ???????????? cross-linking??? ?????? ????????? ????????? ?????? ????????? ???????????????. ?????? pH ???????????? PI ???????????? polymer??? degradation?????? ?????? ???????????? ????????? ???????????? ???????????? ??????. ??????
Kang, Wooseok, Kwon, Young-Nam
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Len opacification following corneal cross-linking for keratoconus in a young woman

Indian Journal of Ophthalmology. Case Reports
Corneal cross-linking (CXL) is indicated for progressive keratoconus to strengthen the corneal stroma by formation of covalent cross-link by exposing the cornea to UVA radiation.
Alexandre Chingan, Yanis Louanchi, Laurence Beral   +2 more
doaj   +1 more source