Results 11 to 20 of about 681,701 (308)

Oncogenic BRCA1,2 Mutations in the Human Lineage—A By-Product of Sexual Selection?

open access: yesBiomedicines, 2023
In this review, we discuss the long-known problem of tissue-specific carcinogenesis in BRCA1 and BRCA2 mutation carriers: while the genes are expressed ubiquitously, increased cancer risk is observed mostly in the breast and ovaries, and to a much lesser
Tatyana V. Korneenko, Nikolay B. Pestov
doaj   +1 more source

At the Crossroads of the cGAS-cGAMP-STING Pathway and the DNA Damage Response: Implications for Cancer Progression and Treatment

open access: yesPharmaceuticals, 2023
The evolutionary conserved DNA-sensing cGAS-STING innate immunity pathway represents one of the most important cytosolic DNA-sensing systems that is activated in response to viral invasion and/or damage to the integrity of the nuclear envelope.
Tatyana V. Korneenko   +6 more
doaj   +1 more source

Systematic review and Meta-analysis comparing modified cross-linking and standard cross-linking for progressive keratoconus [PDF]

open access: yesInternational Journal of Ophthalmology, 2017
AIM: To compare the effectiveness and safety between modified cross-linking (MC) and standard cross-linking (SC) in mild or moderate progressive keratoconus.
Yang Liu   +7 more
doaj   +1 more source

Short- and long-term safety and efficacy of corneal collagen cross-linking in progressive keratoconus: A systematic review and m eta-analysis of randomized controlled trials

open access: yesTaiwan Journal of Ophthalmology, 2023
PURPOSE: The purpose of the study is to evaluate the safety and outcomes of corneal collagen cross-linking (CXL) and different CXL protocols in progressive keratoconus (PK) population at short and long-term.
Phulen Sarma   +15 more
doaj   +1 more source

Clinical outcomes at one year following keratoconus treatment with accelerated transepithelial cross-linking [PDF]

open access: yesInternational Journal of Ophthalmology, 2017
This study evaluated the clinical outcomes in keratoconus corneas following accelerated transepithelial corneal collagen cross-linking (CXL) (Avedro KXL® system, Waltham, MA, USA) over one year of follow-up.
Alberto Artola   +4 more
doaj   +1 more source

Trans-epithelial accelerated corneal cross-linking for keratoconus in children [PDF]

open access: yesInternational Journal of Ophthalmology, 2017
The aim of the study is to evaluate the safety and efficacy of trans-epithelial accelerated corneal cross-linking (TE-ACXL) in children with progressive keratoconus. Retrospective, case-series of 23 eyes of 14 children who underwent TE-ACXL.
Andrew Olivo-Payne   +8 more
doaj   +1 more source

Results of Accelerated Local Cross-Linking in Keratoconus

open access: yesOftalʹmologiâ, 2023
Objective of the study. To analyze the effectiveness of accelerated local corneal cross linking in the treatment of keratoconus (KC). Patients and methods.
H. Khraistin   +4 more
doaj   +1 more source

Recent advances in corneal collagen cross-linking

open access: yesIndian Journal of Ophthalmology, 2017
Corneal collagen cross-linking has become the preferred modality of treatment for corneal ectasia since its inception in late 1990s. Numerous studies have demonstrated the safety and efficacy of the conventional protocol.
Gitansha Shreyas Sachdev   +1 more
doaj   +1 more source

Urine Pyridinium Cross-Links Determination by Beckman Cross Links Kit [PDF]

open access: yesClinical Chemistry, 1997
Increased understanding of bone turnover has led to the development of several biochemical tests of bone metabolism. Among the biochemical indexes of bone resorption is measurement of urinary excretion of pyridinoline (Pyr) and deoxypyridinoline (Dpyr), molecules that cross-link the collagen chains and are released into the systemic circulation after ...
I. Fermo   +3 more
openaire   +3 more sources

Novel Technique of Transepithelial Corneal Cross-Linking Using Iontophoresis in Progressive Keratoconus [PDF]

open access: yes, 2016
In this work, the authors presented the techniques and the preliminary results at 6 months of a randomized controlled trial (NCT02117999) comparing a novel transepithelial corneal cross-linking protocol using iontophoresis with the Dresden protocol for ...
Lombardo, Giuseppe   +4 more
core   +4 more sources

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