Results 91 to 100 of about 490,027 (386)
Artificial Intelligence Enabled Reagent-free Imaging Hematology Analyzer [PDF]
arXiv, 2020 Leukocyte differential test is a widely performed clinical procedure for screening infectious diseases. Existing hematology analyzers require labor-intensive work and a panel of expensive reagents. Here we report an artificial-intelligence enabled reagent-free imaging hematology analyzer (AIRFIHA) modality that can accurately classify subpopulations of
arxiv
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
DEVELOPMENT OF THE REAGENTS AND PROTOCOLS NECESSARY TO ELUCIDATE THE BSP-BINDING REGION OF TYPE I COLLAGEN [PDF]
, 2009 Bone sialoprotein, because of its affinity for the triple-helical type I collagen molecule and increased HA-nucleation potency upon binding collagen in vitro, is postulated to interact with type I collagen in vivo to initiate bone formation. Although the
Langdon, Aaron
core +1 more source
New immunolatex spheres: visual markers of antigens on lymphocytes for scanning electron microscopy [PDF]
, 1975 New immunochemical reagents consisting of antibodies bound to small latex spheres were used as visual markers for the detection and localization of cell surface antigens by scanning electron microscopy.
Dreyer, William J. +3 more
core +2 more sources
PolysaccharidesAlthough diglycidyl ethers of glycols (DEs)—FDA-approved reagents for biomedical applications—were considered unsuitable for the fabrication of chitosan (CH) hydrogels and cryogels, we have recently shown that CH cross-linking with DEs is possible, but ...
Yuliya Privar +4 more
doaj +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Tuning the structure, stability and responsivity of polymeric arsenical nanoparticles using polythiol cross-linkers [PDF]
, 2019 The use of organic arsenicals in polymer chemistry and biomaterials science is limited despite the distinctive and versatile chemistry of arsenic. The interchangeable oxidation states of arsenic and the subsequent changes in chemical properties make it a
Cook, Alexander B. +8 more
core +2 more sources
Reagent: Converting Ordinary Webpages into Interactive Software Agents [PDF]
arXiv, 2018 We introduce Reagent, a technology that readily converts ordinary webpages containing structured data into software agents with which one can interact naturally, via a combination of speech and pointing. Previous efforts to make webpage content manipulable by third-party software components in browsers or desktop applications have generally relied upon
arxiv
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Studies on B Cells in the Fruit-Eating Black Flying Fox (Pteropus alecto)
Frontiers in Immunology, 2019 The ability of bats to act as reservoir for viruses that are highly pathogenic to humans suggests unique properties and functional characteristics of their immune system.
Pravin Periasamy +17 more
doaj +1 more source