Results 41 to 50 of about 183,904 (311)

Effects of Laccase and Transglutaminase on the Physicochemical and Functional Properties of Hybrid Lupin and Whey Protein Powder

Foods
Plant-based protein is considered a sustainable protein source and has increased in demand recently. However, products containing plant-based proteins require further modification to achieve the desired functionalities akin to those present in animal ...
Teguh Santoso, Thao M. Ho, Geerththana Vinothsankar, Kirsi Jouppila, Tony Chen, Adrian Owens, Masoumeh Pourseyed Lazarjani, Mustafa M. Farouk, Michelle L. Colgrave, Don Otter, Rothman Kam, Thao T. Le   +11 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Photochromic sensitivity of modified bacteriorhodopsin films for molecular electronics devices

Технологія та конструювання в електронній апаратурі, 2005
In the search for materials for molecular electronics, the possibility of modifying bacteriorhodopsin (BR) films with bifunctional cross-linking reagents has been investigated.
G. E. Adamov, E. P. Grebennikov, A. G. Devyatkov   +2 more
doaj  

Mast cell subsets and their functional modulation by the Acanthocheilonema viteae product ES-62 [PDF]

, 2013
ES-62, an immunomodulator secreted by filarial nematodes, exhibits therapeutic potential in mouse models of allergic inflammation, at least in part by inducing the desensitisation of Fc휀RI-mediated mast cell responses.
Al-Riyami, Lamyaa, Ball, Dimity, Bell, Kara, Coates, Michelle, Harnett, Margaret, Harnett, William, Rzepecka, Justyna, Tay, Hwee Kee   +7 more
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Enhanced Bonding To Caries Dentin Using An Isocyanate-Based Primer

International Dental Journal
Aim or purpose: In minimally invasive dentistry, the principle behind cavity preparation is to remove external caries-infected dentin (CID) and preserve internal caries-affected dentin (CAD) and sound dentin (SD).
Luna Tang, Ji-Hua Chen
doaj   +1 more source

Flexible aromatic disulfide monomers for high-performance self-healable linear and cross-linked poly(urethane-urea) coatings [PDF]

, 2019
Implementation of the self-healing concept in coatings is challenging because they have to combine mechanical strength and chain mobility. This challenge is addressed in this work by studying the effect of the polymer microstructure on the mechanical ...
Asua González, José María, Ballard, Nicholas, Fernández San Martín, Mercedes, Nevejans, Sil, Reck, Bernd   +4 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Cross-linking da cornea: protocolo padrão

Revista Brasileira de Oftalmologia
RESUMO O objetivo desta revisão é de determinar as indicações e eficácia da cirurgia que promove novas ligações covalentes entre as fibras de colágeno da córnea, conhecida como Cross-Linking (CXL), assim como esclarecer seus objetivos. O ceratocone é uma
Marcony R. Santhiago
doaj   +1 more source

Simplified three-dimensional tissue clearing and incorporation of colorimetric phenotyping. [PDF]

, 2016
Tissue clearing methods promise to provide exquisite three-dimensional imaging information; however, there is a need for simplified methods for lower resource settings and for non-fluorescence based phenotyping to enable light microscopic imaging ...
Chen, Harrison, Cheng, Michelle, Di Carlo, Dino, Ding, Yichen, Eguchi, Daniel, Hsiai, Tzung K, Huang, Vincent, Kim, Jocelyn T, Kulkarni, Rajan P, Ma, Jianguo, Nakano, Atsushi, Sung, Kevin, Yang, Cindy F   +12 more
core   +2 more sources