Results 171 to 180 of about 5,402,153 (218)

Editorial: Synthetic biology approaches for biocatalytic production of value-added chemicals. [PDF]

Front Bioeng Biotechnol
Peng H, Patel SKS, Lee JK.
europepmc   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

A modular verification and validation framework for hybrid-capture next-generation sequencing HLA typing in clinical histocompatibility laboratories. [PDF]

Front Genet
Scarpa A, Ferrarese D, Guidotti S, Scaglia V, Rossi A.   +4 more
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Building a new ecosystem for digital-intelligent teaching of veterinary infectious diseases in southwest Chinese universities: theoretical framework and practical pathways. [PDF]

Front Vet Sci
Wang X, Li M, Du Y, Yang H, Ran J, Zhang H.   +5 more
europepmc   +1 more source

Revealing the Underlying Mechanisms in Performance Enhancement of Shellular Lattice Electrodes During Anion Exchange Membrane Water Electrolysis Process

Advanced Science, EarlyView.
Micro laser powder bed fusion enables architected nickel shellular lattice gas diffusion layers for anion exchange membrane water electrolysis. Among regular open cell geometries, the Gyroid lattice promotes bubble release, convective reactant replenishment and continuous electron transport, delivering low overpotentials, enhanced charge transfer and ...
Tianxiao Niu, Rui Li, Xiao Chen, Deyong Sun, Tianyu Gao, Junhao Ding, Shuo Qu, Xu Song   +7 more
wiley   +1 more source

Integrated design process of Chinese character furniture through regular script. [PDF]

PLoS One
Li J, Shi J, Wei Y, Yan K.
europepmc   +1 more source

Magnetic Water Cleaning of Estrogens via Tight yet Dynamic Binding to Nanoparticles

Advanced Science, EarlyView.
Micropollution is one of the big challenges humanity faces with estrogen hormones being emerging pollutants of concern. Here, a supramolecular design strategy is presented that generates a simple nano‐adsorbent material to magnetically remove low‐concentrated estrogens from water.
Lukas Müller, Philip Maier, Dustin Vivod, Wenke Müller, Nikolaj Lopatik, Theresa Maria Schichtl, Julia Fröhlich, Irene Kraus, Marten Huck, Wieland Corts, Clodomiro Cafolla, Lukas Ruhm, Henrik Gaß, Johannes Voß, Jiwon Byun, Linda Rockmann, Guido Grundmeier, Kislon Voïtchovsky, Hans‐Georg Steinrück, Erdmann Spiecker, Sevim Dalabasmaz, Monika Pischetsrieder, Eike Brunner, Ralf Schweins, Dirk Zahn, Marcus Halik   +25 more
wiley   +1 more source

Editorial: The importance of faculty development in medical education. [PDF]

Front Genet
Pereza N, Hauser G, Jovanović P.
europepmc   +1 more source

Artificial Intelligence‐Empowered Single‐Cell Phenotyping for Rapid, Automated Pathogen Diagnostics

Advanced Science, EarlyView.
This work presents an integrated diagnostic platform that combines microfluidic single‐cell bacterial detection with artificial intelligence‐driven analysis for rapid antimicrobial susceptibility testing. Single‐cell phenotyping enables assessment of antibiotic response in only a few cell replication cycles, while AI analysis supports precise bacterial
Sabita Khadka, Bushra Raahat, Spyros Tragoudas, Hui Li   +3 more
wiley   +1 more source