Results 191 to 200 of about 26,382 (222)

How Advanced Artificial Intelligence Technologies Shape Drug–Drug and Drug–Target Interaction Modeling

Advanced Science, EarlyView.
This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley   +1 more source

Grief modular group therapy: theoretical bases and pilot study of a new bereavement intervention programme in China. [PDF]

Eur J Psychotraumatol
Zhou N, Tang S, Zhou J, Guo L, Junlian L, Situ B, Liu X.   +6 more
europepmc   +1 more source

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

Advanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu, Huan Liu, Songyin Zhao, Lei Qin, Jiarui Li, Jun Wang, Zixuan Dai, Jie Gu, Yan Xu, Feiran Li, Yao Nie   +10 more
wiley   +1 more source

From artificial to organic: Rethinking the roots of intelligence for digital health. [PDF]

PLOS Digit Health
Ghimire P, Ashkan K.
europepmc   +1 more source

Scenario-based functional modularization framework for consumer electronics using MFD and AHP: A case study on audio products. [PDF]

PLoS One
Wu Z, Zhang J.
europepmc   +1 more source

Design of a Novel, Modular, Mouth Retractor: A Concept Testing Study. [PDF]

Acta Med Philipp
Aljibe MSO, Apacible AMC, Fullante PB.
europepmc   +1 more source

My Cosmos: development, clinical protocol, and preliminary usability of a gamified transdiagnostic digital CBT platform. [PDF]

Front Psychiatry
Del Vecchio S, Barlattani T, Carcione A, Pacitti F, Recchioni M.   +4 more
europepmc   +1 more source

Revolutionizing clinical skills training with Generative AI: the Intelligent Inquiry Training System framework. [PDF]

Front Med (Lausanne)
Liu H, Cheng H, Zhang Y, Huang Y, Tan D, Wang Z, Zhang F, Ming S.   +7 more
europepmc   +1 more source

Autonomous microfluidic labs: progress and prospects.

Lab Chip
Damir S, Delgado-Licona F, deMello A, Abolhasani M.   +3 more
europepmc   +1 more source