Results 1 to 10 of about 2,187,639 (196)
The method quality of cross-over studies involved in Cochrane Systematic Reviews. [PDF]
BackgroundIt is possible that cross-over studies included in current systematic reviews are being inadequately assessed, because the current risk of bias tools do not consider possible biases specific to cross-over design.
Hong Ding+5 more
doaj +2 more sources
Effect of acute hyperglycemia on left ventricular contractile function in diabetic patients with and without heart failure: two randomized cross-over studies. [PDF]
BackgroundIt is unknown whether changes in circulating glucose levels due to short-term insulin discontinuation affect left ventricular contractile function in type 2 diabetic patients with (T2D-HF) and without (T2D-nonHF) heart failure.Materials and ...
Roni Nielsen+5 more
doaj +2 more sources
Cross-national research on adolescent mental health: a systematic review comparing research in low, middle and high-income countries [PDF]
Background Although 90% of the global adolescent population resides in low and middle-income countries (LMICs), cross-national mental health research has primarily focused on high-income countries.
Xiao Zhang+14 more
doaj +2 more sources
Blockchain technology and its applications have recently become a research hotspot. Its three core technologies, distributed ledger, smart contract, and consensus mechanism, provide trust-enhancing features such as tamper-proof records, full traceability,
Meiwen Guo+6 more
doaj +1 more source
Effects of Reducing Indoor Air Particles on Cardiovascular and Respiratory Physiological Indexes in the Elderly: a Randomized Crossover Controlled Trial [PDF]
Background Exposure to indoor air particles pollution increases the incidence and mortality of respiratory and cardiovascular diseases, especially in the elderly population.
ZHOU Min, ZHENG Ziguang, YOU Hongyu, GUO Miao, YU Wei, YANG Xu
doaj +1 more source
Pharmacokinetic boosting of olaparib: A randomised, cross-over study (PROACTIVE-study) [PDF]
Pharmacokinetic (PK) boosting is the intentional use of a drug-drug interaction to enhance systemic drug exposure. PK boosting of olaparib, a CYP3A-substrate, has the potential to reduce PK variability and financial burden. The aim of this study was to investigate equivalence of a boosted, reduced dose of olaparib compared to the non-boosted standard ...
Overbeek, Joanneke K.+13 more
openaire +4 more sources
Exemption from informed consent: When it is possible in investigational product and drug trials?
One of the most important ethical step in conducting investigational product trials or drug trials is obtaining informed consent from the participants.
Swati Verma
doaj +1 more source
Background and aims Studies concerning the impact of air temperature on esophagogastric variceal bleeding (EGVB) have yielded conflicting results. Our study aimed to evaluate the correlation between air temperature and EGVB.
Jianhong Chen+8 more
doaj +1 more source
Objective: This review is to compare patient-satisfaction with ball-type overdenture attachment systems with others attachment systems. Material and methods: This study was registered in PROSPERO (CRD42018097234) and adheres the PRISMA guidelines ...
Cleber Davi Del Rei Daltro Rosa+5 more
doaj +1 more source
Background The chronic inflammation in patients with rheumatoid arthritis (RA) increases the risk for cardiovascular diseases (CVD). The contribution of diet as a risk factor for CVD among these patients is however not fully understood.
Erik Hulander+6 more
doaj +1 more source