Results 1 to 10 of about 2,187,639 (196)

The method quality of cross-over studies involved in Cochrane Systematic Reviews. [PDF]

open access: yesPLoS ONE, 2015
BackgroundIt is possible that cross-over studies included in current systematic reviews are being inadequately assessed, because the current risk of bias tools do not consider possible biases specific to cross-over design.
Hong Ding   +5 more
doaj   +2 more sources

Effect of acute hyperglycemia on left ventricular contractile function in diabetic patients with and without heart failure: two randomized cross-over studies. [PDF]

open access: yesPLoS ONE, 2013
BackgroundIt is unknown whether changes in circulating glucose levels due to short-term insulin discontinuation affect left ventricular contractile function in type 2 diabetic patients with (T2D-HF) and without (T2D-nonHF) heart failure.Materials and ...
Roni Nielsen   +5 more
doaj   +2 more sources

Cross-national research on adolescent mental health: a systematic review comparing research in low, middle and high-income countries [PDF]

open access: yesBMJ Global Health
Background Although 90% of the global adolescent population resides in low and middle-income countries (LMICs), cross-national mental health research has primarily focused on high-income countries.
Xiao Zhang   +14 more
doaj   +2 more sources

Application of Blockchain Technology in Environmental Health: Literature Review and Prospect of Visualization Based on CiteSpace

open access: yesTechnologies, 2022
Blockchain technology and its applications have recently become a research hotspot. Its three core technologies, distributed ledger, smart contract, and consensus mechanism, provide trust-enhancing features such as tamper-proof records, full traceability,
Meiwen Guo   +6 more
doaj   +1 more source

Effects of Reducing Indoor Air Particles on Cardiovascular and Respiratory Physiological Indexes in the Elderly: a Randomized Crossover Controlled Trial [PDF]

open access: yesZhongguo quanke yixue, 2023
Background Exposure to indoor air particles pollution increases the incidence and mortality of respiratory and cardiovascular diseases, especially in the elderly population.
ZHOU Min, ZHENG Ziguang, YOU Hongyu, GUO Miao, YU Wei, YANG Xu
doaj   +1 more source

Pharmacokinetic boosting of olaparib: A randomised, cross-over study (PROACTIVE-study) [PDF]

open access: yesEuropean Journal of Cancer, 2023
Pharmacokinetic (PK) boosting is the intentional use of a drug-drug interaction to enhance systemic drug exposure. PK boosting of olaparib, a CYP3A-substrate, has the potential to reduce PK variability and financial burden. The aim of this study was to investigate equivalence of a boosted, reduced dose of olaparib compared to the non-boosted standard ...
Overbeek, Joanneke K.   +13 more
openaire   +4 more sources

Exemption from informed consent: When it is possible in investigational product and drug trials?

open access: yesSaudi Journal of Anaesthesia, 2021
One of the most important ethical step in conducting investigational product trials or drug trials is obtaining informed consent from the participants.
Swati Verma
doaj   +1 more source

Association between air temperature and emergency admission for esophagogastric variceal bleeding: a case-crossover study in Beijing, China

open access: yesBMC Gastroenterology, 2023
Background and aims Studies concerning the impact of air temperature on esophagogastric variceal bleeding (EGVB) have yielded conflicting results. Our study aimed to evaluate the correlation between air temperature and EGVB.
Jianhong Chen   +8 more
doaj   +1 more source

Do ball-type attachment systems for overdenture result in better patient-satisfaction? A systematic review of randomized crossover clinical trial

open access: yesSaudi Dental Journal, 2021
Objective: This review is to compare patient-satisfaction with ball-type overdenture attachment systems with others attachment systems. Material and methods: This study was registered in PROSPERO (CRD42018097234) and adheres the PRISMA guidelines ...
Cleber Davi Del Rei Daltro Rosa   +5 more
doaj   +1 more source

Diet intervention improves cardiovascular profile in patients with rheumatoid arthritis: results from the randomized controlled cross-over trial ADIRA

open access: yesNutrition Journal, 2021
Background The chronic inflammation in patients with rheumatoid arthritis (RA) increases the risk for cardiovascular diseases (CVD). The contribution of diet as a risk factor for CVD among these patients is however not fully understood.
Erik Hulander   +6 more
doaj   +1 more source

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