Results 171 to 180 of about 2,187,738 (295)

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Global climate migration is a story of who and not just how many. [PDF]

Nat Commun
Benveniste H, Huybers P, Proctor J.
europepmc   +1 more source

A BIOMETRICAL STUDY OF CROSSING OVER. ON THE MECHANISM OF CROSSING OVER IN THE THIRD CHROMOSOME OF DROSOPHILA MELANOGASTER

Genetics, 1919
openaire   +3 more sources

A CYTOGENETIC STUDY OF CROSSING OVER IN INVERSION HETEROZYGOTES OF DROSOPHILA MELANOGASTER [PDF]

Genetics, 1960
John C. Lucchesi, Claude W. Hinton
openaire   +2 more sources

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Prediabetes in adult Saudis: a systematic review & meta-analysis of prevalence studies (2000-2024). [PDF]

PeerJ
Mohieldein A, Baig HA, Elhabiby M, Almushawwah A, Mahfouz MS, Khirelsied AH, Abdelmarouf N, Modawe G.   +7 more
europepmc   +1 more source

Clinical trial: a randomized controlled cross‐over study of flupenthixol + melitracen in functional dyspepsia [PDF]

, 2008
Jana G. Hashash, Hasan Abdulbaki, Cecilio Azar, Ihab I. El-Hajj, Lara El Zahabi, Hani F. Chaar, Ala I. Sharara   +6 more
openalex   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Core Symptoms and Dynamic Interactions of Depressive Symptoms in Older Chinese Adults: A Longitudinal Network Analysis. [PDF]

Depress Anxiety
Feng Y, Chen L, Yuan Q, Ma L, Zhao W, Bai L, Chen J.   +6 more
europepmc   +1 more source

Remifentanil-propofol analgo-sedation shortens duration of ventilation and length of ICU stay compared to a conventional regimen: a centre randomised, cross-over, open-label study in the Netherlands [PDF]

, 2008
F. Willem Rozendaal, Peter E. Spronk, Ferdinand F. Snellen, Adri Schoen, Arthur R. H. van Zanten, Norbert A. Foudraine, Paul Mulder, Jan Bakker   +7 more
openalex   +1 more source