Results 11 to 20 of about 2,115,171 (296)

The method quality of cross-over studies involved in Cochrane Systematic Reviews. [PDF]

PLoS ONE, 2015
BackgroundIt is possible that cross-over studies included in current systematic reviews are being inadequately assessed, because the current risk of bias tools do not consider possible biases specific to cross-over design.
Hong Ding, Guang Li Hu, Xue Yan Zheng, Qing Chen, Diane Erin Threapleton, Zeng Huan Zhou   +5 more
doaj   +2 more sources

Effect of acute hyperglycemia on left ventricular contractile function in diabetic patients with and without heart failure: two randomized cross-over studies. [PDF]

PLoS ONE, 2013
BackgroundIt is unknown whether changes in circulating glucose levels due to short-term insulin discontinuation affect left ventricular contractile function in type 2 diabetic patients with (T2D-HF) and without (T2D-nonHF) heart failure.Materials and ...
Roni Nielsen, Helene Nørrelund, Ulla Kampmann, Hans Erik Bøtker, Niels Møller, Henrik Wiggers   +5 more
doaj   +2 more sources

Spironolactone in pulmonary arterial hypertension: results of a cross‐over study [PDF]

Pulmonary Circulation, 2020
The renin–angiotensin–aldosterone system is implicated in the pathophysiology of pulmonary arterial hypertension. We undertook this study to determine the effects of spironolactone, a mineralocorticoid receptor blocker, on collagen metabolism in pulmonary arterial hypertension patients.
Zeenat Safdar, Adaani Frost, Arya Basant, Anita Deswal, E. O’Brian Smith, Mark Entman   +5 more
openaire   +5 more sources

Acceptability of Binaural Hearing Aids: A Cross-Over Study [PDF]

Journal of the Royal Society of Medicine, 1991
Using screening questionnaires we were able to detect individuals aged 50–65 years with hearing disability in a general practice population. Those who had better ear hearing levels of 30 dB or worse were invited to take place in a cross-over study comparing the acceptability of a monaural or binaural hearing-aid fitting. Fifty-five per cent ultimately
A. C. Davis, S. D. G. Stephens, D. E. Callaghan, A. Rayment, R. Meredith, S. Hogan   +5 more
openaire   +3 more sources

Pharmacokinetic boosting of olaparib: A randomised, cross-over study (PROACTIVE-study)

European Journal of Cancer, 2023
Pharmacokinetic (PK) boosting is the intentional use of a drug-drug interaction to enhance systemic drug exposure. PK boosting of olaparib, a CYP3A-substrate, has the potential to reduce PK variability and financial burden. The aim of this study was to investigate equivalence of a boosted, reduced dose of olaparib compared to the non-boosted standard ...
Overbeek, Joanneke K., Guchelaar, Niels A.D., Mohmaed Ali, Ma Ida, Ottevanger, Petronella B., Bloemendal, Haiko J., Koolen, Stijn L.W., Mathijssen, Ron H.J., Boere, Ingrid A., Hamberg, Paul, Huitema, Alwin D.R., Sonke, Gabe S., Opdam, Frans L., ter Heine, Rob, van Erp, Nielka P.   +13 more
openaire   +5 more sources

Alcohol and risk of admission to hospital for unintentional cutting or piercing injuries at home: a population-based case-crossover study

BMC Public Health, 2011
Background Cutting and piercing injuries are among the leading causes of unintentional injury morbidity in developed countries. In New Zealand, cutting and piercing are second only to falls as the most frequent cause of unintentional home injuries ...
Thornley Simon, Kool Bridget, Robinson Elizabeth, Marshall Roger, Smith Gordon S, Ameratunga Shanthi   +5 more
doaj   +1 more source

Analysis of the velocity distribution in different types of ventilation system ducts [PDF]

EPJ Web of Conferences, 2018
The paper presents the results obtained during the preliminary studies of circular and rectangular ducts before testing the properties elements (elbows, tees, etc.)of rectangular with rounded corners ducts.
Peszyński Kazimierz, Olszewski Lukasz, Smyk Emil, Perczyński Daniel   +3 more
doaj   +2 more sources

Online-haemodiafiltration vs. conventional haemodialysis: a cross-over study [PDF]

BMC Nephrology, 2015
The main short-term advantages of haemodiafiltration (HDF) are supposedly better removal of Beta2-microglobulin (ß2-m) and phosphate, and better haemodynamic stability. The main disadvantage is higher costs. The aim of the study was to compare the clinical and biological parameters associated with HDF and high-flux haemodialysis (HD), using a cross ...
Brice Mayor, Jean-Marc Hurot, Patrik Deleaval, Christie Lorriaux, Guillaume Jean   +4 more
openaire   +3 more sources

Cross-national analyses require additional controls to account for the non-independence of nations

Nature Communications, 2023
Cross-national analyses test hypotheses about the drivers of variation in national outcomes. However, since nations are connected in various ways, such as via spatial proximity and shared cultural ancestry, cross-national analyses often violate ...
Scott Claessens, Thanos Kyritsis, Quentin D. Atkinson   +2 more
doaj   +1 more source

Environmental triggers of COPD symptoms: a case cross-over study [PDF]

BMJ Open Respiratory Research, 2017
IntroductionThis study investigated the hypothesis that common environmental chemical exposures with known irritant or sensitising properties trigger exacerbations for patients with chronic obstructive pulmonary disease (COPD).MethodsWe conducted a case cross-over study in 168 patients with COPD who were members of a disease management group in central
Richard Rosiello, David Kriebel, Rebecca Gore, Susan R. Sama, Rebecca DeVries   +4 more
openaire   +2 more sources