Results 41 to 50 of about 2,187,738 (295)
THE OWN STRESSES INFLUENCE ON SCALE EFFECT IN CONCRETE
The experimental technique and the experiment results on the influence of own stresses unevenly distributed over cross section on materials strength and on scale effect are presented.
Aleksey Fenko+4 more
doaj +1 more source
Azathioprine in Rheumatoid Arthritis A Double‐Blind, Cross‐Over Study [PDF]
AbstractSeventeen patients with classic rheumatoid arthritis resistant to conventional therapy were treated in a double‐blind, cross‐over study with azathioprine (2.0 to 2.5 mg/kg/day) and placebo for two 16‐week periods. Patients receiving azathioprine showed significant improvement in articular index, joint count, grip strength and effusions ...
Murray B. Urowitz+4 more
openaire +3 more sources
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Knowledge of cytology results affects the performance of colposcopy: a crossover study
Objective To determine whether knowledge of cytology affects the colposcopist’s diagnostic accuracy in the identification of cervical intraepithelial neoplasia grade 2 and worse (≥ CIN2).
Eva Lalande+11 more
doaj +1 more source
BackgroundIn Southeast Asia, the prevalence of multimorbidity is gradually increasing. This paper aimed to investigate the association between educational level and multimorbidity among over 15-years old adults in Southeast Asia.MethodsWe conducted a ...
Xiyu Feng+2 more
doaj +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling+4 more
wiley +1 more source
Background Nigella sativa (NS) oil has been found to have advantageous benefits in the management of inflammation and obesity. This study investigated the effect of NS supplementation on blood mRNA expressions and serum levels of IL-1β, IL-6, leptin, and
Elham Razmpoosh+6 more
doaj +1 more source
A meta-analysis was performed to quantify the magnitude and nature of the association between adjuvant chemotherapy and performance on a range of cognitive domains among breast cancer patients.
Miyuki eOno+7 more
doaj +1 more source