Results 41 to 50 of about 12,943,494 (381)

Online-haemodiafiltration vs. conventional haemodialysis: a cross-over study [PDF]

BMC Nephrology, 2015
The main short-term advantages of haemodiafiltration (HDF) are supposedly better removal of Beta2-microglobulin (ß2-m) and phosphate, and better haemodynamic stability. The main disadvantage is higher costs. The aim of the study was to compare the clinical and biological parameters associated with HDF and high-flux haemodialysis (HD), using a cross ...
Jean, Guillaume, Hurot, Jean-Marc, Deleaval, Patrik, Mayor, Brice, Lorriaux, Christie   +4 more
openaire   +2 more sources

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine, Béliard Sophie, Renard Cécile, Caussy Cyrielle, Hamidou Zeinab, Romano David, Gacem Mélanie, Petit Arnaud, Saultier Paul, Borentain Patrick, Michel Gérard   +10 more
wiley   +1 more source

Determination of the Pharmacokinetics and Pharmacodynamics of Isoniazid, Rifampicin, Pyrazinamide and Ethambutol in a Cross-Over Cynomolgus Macaque Model of Mycobacterium tuberculosis Infection

Pharmaceutics, 2022
Innovative cross-over study designs were explored in non-human primate (NHP) studies to determine the value of this approach for the evaluation of drug efficacy against tuberculosis (TB). Firstly, the pharmacokinetics (PK) of each of the drugs Isoniazid (
Laura Sibley, Andrew D. White, Charlotte Sarfas, Jennie Gullick, Fergus Gleeson, Faye Lanni, Simon Clark, Emma Rayner, Santiago Ferrer-Bazaga, Fatima Ortega-Muro, Laura Alameda, Joaquin Rullas, Veronica Sousa, Marisa Martinez, Inigo Angulo-Barturen, Adolfo Garcia, Juan José Vaquero, Henry E. Pertinez, Geraint Davies, Mike Dennis, Ann Williams, Sally Sharpe   +21 more
doaj   +1 more source

Survey strategy optimization for the Atacama Cosmology Telescope [PDF]

, 2016
In recent years there have been significant improvements in the sensitivity and the angular resolution of the instruments dedicated to the observation of the Cosmic Microwave Background (CMB).
Alonso, D., Bond, J. R., Calabrese, E., Choi, S. K., Crowley, K. T., De Bernardis, F., Devlin, M., Dunkley, J., Gallardo, P. A., Hasselfield, M., Henderson, S. W., Hilton, M., Hlozek, R., Ho, S. P., Huffenberger, K., Koopman, B. J., Kosowsky, A., Louis, T., Madhavacheril, M. S., McMahon, J., Naess, S., Nati, F., Newburgh, L., Niemack, M. D., Page, L. A., Salatino, M., Schillaci, A., Schmitt, B. L., Sehgal, N., Sievers, J. L., Simon, S. M., Spergel, D. N., Staggs, S. T., Stevens, J. R., van Engelen, A., Vavagiakis, E. M., Wollack, E. J.   +36 more
core   +2 more sources

Relation of Adverse Childhood Experiences to Clinical and Patient‐Reported Outcomes for Adults With Sickle Cell Disease: A Registry Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adverse childhood experiences (ACEs) are stressful or traumatic events prior to age 18 that are known to have a lasting impact on individuals’ health and well‐being. There is a gap in understanding the relationship between ACEs and Other Life Stressors and health status for adults with sickle cell disease (SCD).
Marsha Treadwell, Jessica Liang, Liliana Preiss, Angela Rivers, Jane S. Hankins, Allison King, Justin Williams, Michael B. Potter, Danielle Hessler   +8 more
wiley   +1 more source

Efficacy and Feasibility of OptraDam^® Plus Versus Conventional Rubber Dams in Preclinical Simulation Training: A Randomized Crossover Trial

Dentistry Journal
Background/Objectives: Despite clear benefits, conventional rubber dam use remains low due to barriers that often originate during undergraduate training. To examine a potential approach to mitigating these barriers, this study evaluated the efficacy and
Fahad BaHammam, Mohammed Alsuhaibani, Faisal Almutairi, Sultan Aldakhil, Shug Albarrak, Lulwah Alreshaid, Fathima Farook   +6 more
doaj   +1 more source

Differential mortality and wealth accumulation [PDF]

, 1995
The issue of asset accumulation and decumulation is central to the life cycle theory of consumer behavior and to many policy questions. One of the main implications of the life cycle model is that assets are decumulated in the last part of life.
Attanasio, O., Hoynes, H.W.
core   +1 more source

Azathioprine in Rheumatoid Arthritis A Double‐Blind, Cross‐Over Study [PDF]

Arthritis & Rheumatism, 1973
AbstractSeventeen patients with classic rheumatoid arthritis resistant to conventional therapy were treated in a double‐blind, cross‐over study with azathioprine (2.0 to 2.5 mg/kg/day) and placebo for two 16‐week periods. Patients receiving azathioprine showed significant improvement in articular index, joint count, grip strength and effusions ...
M B, Urowitz, D A, Gordon, H A, Smythe, W, Pruzanski, M A, Ogryzio   +4 more
openaire   +2 more sources

What to Do When Medical Evidence Can Only Be Generated Through Routine Data: An Example From Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt, Antje Walz, Dietrich Knoerzer   +2 more
wiley   +1 more source

Clinical effectiveness of subsensory sacral neuromodulation in adults with faecal incontinence: the SUBSoNIC crossover RCT and mechanistic study

Efficacy and Mechanism Evaluation
Trial design Randomised, multicentre, double-blind crossover trial (with 2 × 16-week periods) of active neurostimulation versus sham stimulation with subsequent open-label follow-up to 58 weeks. Embedded mechanistic sub-study using magnetoencephalography
Paul F Vollebregt, Yan Li Goh, Claire L Chan, Thomas Dudding, Paul Furlong, Shaheen Hamdy, Joanne Haviland, Richard Hooper, James Jones, Eleanor McAlees, Christine Norton, P Ronan O’Connell, S Mark Scott, Natasha Stevens, Kerry Tubby, Sian Worthen, Yuk Lam Wong, Charles H Knowles   +17 more
doaj   +1 more source