Results 51 to 60 of about 2,115,171 (296)

What Comes First Metacognition or Negative Emotion? A Test of Temporal Precedence

open access: yesFrontiers in Psychology, 2019
The Self-Regulatory Executive Function model predicts that emotional symptoms and metacognition can causally affect each other. Crucially, for the model metacognition must cause emotion disorder symptoms. Therefore, in time-series data involving repeated
Lora Capobianco   +5 more
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Venous ulceration: A cross-over study from nonoperative to operative treatment [PDF]

open access: yesJournal of Vascular Surgery, 1996
This study compared 3 years of nonoperative therapy in a vascular clinic (1991 to 1993) with a proactive approach to diagnosis and operative treatment (1994 to 1995).In the first period, 11 compliant men 48 to 69 years of age (average, 55 years) were treated without surgery using Unna's boot dressing, compression wound care, and patient education.
Ralph G. DePalma, Donna L. Kowallek
openaire   +2 more sources

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

GOCE sensitivity studies in terms of cross-over analysis [PDF]

open access: yes, 2009
The GOCE (Gravity field and steady-state Ocean Circulation Explorer) satellite, launched on 17 March 2009, for the first time applies satellite gravity gradiometry (SGG) to recover the Earth's gravity field with cm accuracy at a resolution of 100km.
openaire   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Knowledge and beliefs about the Red Cross: Perspectives of community members and Red Cross workers in San Ramón, Alajuela, Costa Rica

open access: yesCuadernos de investigación UNED, 2016
In Costa Rica, the Red Cross provides most pre-hospital emergency care and transport. Very few studies have investigated extra-hospital emergency care in Costa Rica so this study aimed to fill this gap through interviews with community members, surveys ...
Tela Ebersole, Anabelle Alfaro Obando
doaj   +1 more source

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