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Implications of Cross-Reactivity and Cross-Protection for Pneumococcal Vaccine Development [PDF]

Vaccines
Pneumococcal vaccines are a cornerstone for the prevention of pneumococcal diseases, reducing morbidity and mortality in children and adults worldwide.
Kristen Feemster, William P. Hausdorff, Natalie Banniettis, Heather Platt, Priscilla Velentgas, Alejandra Esteves-Jaramillo, Robert L. Burton, Moon H. Nahm, Ulrike K. Buchwald   +8 more
doaj   +3 more sources

Evidence for cross-protection but not type-replacement over the 11 years after human papillomavirus vaccine introduction [PDF]

Human Vaccines & Immunotherapeutics, 2019
Examination of cross-protection and type replacement after human papillomavirus (HPV) vaccine introduction is essential to guide vaccination recommendations and policies.
Courtney Covert, Lili Ding, Darron Brown, Eduardo L. Franco, David I Bernstein, Jessica A. Kahn   +5 more
doaj   +3 more sources

A New Era for Mild Strain Cross-Protection

Viruses, 2019
Societal and environmental pressures demand high-quality and resilient cropping plants and plant-based foods grown with the use of low or no synthetic chemical inputs.
Katrin Pechinger, Kar Mun Chooi, Robin M. MacDiarmid, Scott J. Harper, Heiko Ziebell   +4 more
doaj   +2 more sources

Enhancing cross-protection against influenza by heterologous sequential immunization with mRNA LNP and protein nanoparticle vaccines. [PDF]

Nat Commun
Enhancing influenza vaccine cross-protection is imperative to alleviate the significant public health burden of influenza. Heterologous sequential immunization may synergize diverse vaccine formulations and routes to improve vaccine potency and breadth ...
Dong C, Zhu W, Wei L, Kim JK, Ma Y, Kang SM, Wang BZ.   +6 more
europepmc   +2 more sources

Efficacy evaluation of a bivalent subunit vaccine against epidemic PEDV heterologous strains with low cross-protection. [PDF]

J Virol
Variant Porcine epidemic diarrhea virus (PEDV), which causes diarrhea and high mortality in piglets, has become a major pathogen, and co-epidemics of different subtypes of the virus have become a very thorny problem for the clinical prevention and ...
Song X, Li Y, Wang C, Zhao Y, Yang S, Guo R, Hu M, Sun M, Zhang G, Li Y, Wang Y, Liu S, Shen Y, Li C, Zhang X, Li J, Fan B, Li B.   +17 more
europepmc   +2 more sources

Vaccination against SARS-CoV-2 provides low-level cross-protection against common cold coronaviruses in mouse and non-human primate animal models [PDF]

Journal of Virology
The common cold coronaviruses are a source of ongoing morbidity and mortality particularly among elderly and immunocompromised individuals. While cross-reactive immune responses against multiple coronaviruses have been described following severe acute ...
Maedeh Naghibosadat, George Giorgi Babuadze, Yanlong Pei, Jacklyn Hurst, Elsa Salvant, Kayla Gaete, Mia Biondi, Badru Moloo, Alyssa Goldstein, Stacey Avery, Kathleen Ma, Anna Pietraszek, Sarah K. Wootton, Assad Alhaboub, Benjamin Martin, Samira Mubareka, Juan Corredor, Azmiri Sultana, Adebayo Adeekoa, Patrick Budylowski, Mario Ostrowski, Jesse Chao, Eva Nagy, Robert Kozak   +23 more
doaj   +2 more sources

Mechanisms of Flavivirus Cross-Protection against Yellow Fever in a Mouse Model [PDF]

Viruses
The complete lack of yellow fever virus (YFV) in Asia, and the lack of urban YFV transmission in South America, despite the abundance of the peridomestic mosquito vector Aedes (Stegomyia.) aegypti is an enigma. An immunologically naïve population of over
Divya P. Shinde, Jordyn Walker, Rachel A. Reyna, Dionna Scharton, Brooke Mitchell, Ennid Dulaney, Srinivisa Reddy Bonam, Haitao Hu, Jessica A. Plante, Kenneth S. Plante, Scott C. Weaver   +10 more
doaj   +2 more sources

Cross-protection induced by VA-MENGOC-BC® vaccine [PDF]

Human Vaccines & Immunotherapeutics, 2018
I would like to comment on the article "Commentary: Impact of meningococcal group B OMV vaccines, beyond their brief", DOI: 10.1080/21645515.2017.1381810. The author states that meningococcal group B OMVs vaccines -such as VA-MENGOC-BC®- may induce moderate protection against Neisseria gonorrhoeae. I agree. However, the author states that "there was no
R. Ochoa-Azze
openaire   +4 more sources

Vaccine approaches conferring cross-protection against influenza viruses [PDF]

Expert Review of Vaccines, 2017
Annual vaccination is one of the most efficient and cost-effective strategies to prevent and control influenza epidemics. Most of the currently available influenza vaccines are strong inducers of antibody responses against viral surface proteins, hemagglutinin (HA) and neuraminidase (NA), but are poor inducers of cell-mediated immune responses against ...
Sai V Vemula, Ekramy E Sayedahmed, Suryaprakash Sambhara, Suresh K Mittal   +3 more
openaire   +4 more sources

Challenging boundaries: is cross-protection evaluation necessary for African swine fever vaccine development? A case of oral vaccination in wild boar [PDF]

Frontiers in Immunology
African swine fever (ASF) poses a significant threat to domestic pigs and wild boar (Sus scrofa) populations, with the current epidemiological situation more critical than ever. The disease has spread across five continents, causing devastating losses in
Estefanía Cadenas-Fernández, Estefanía Cadenas-Fernández, Sandra Barroso-Arévalo, Sandra Barroso-Arévalo, Aleksandra Kosowska, Aleksandra Kosowska, Marta Díaz-Frutos, Marta Díaz-Frutos, Carmina Gallardo, Antonio Rodríguez-Bertos, Antonio Rodríguez-Bertos, Jaime Bosch, Jaime Bosch, Jose M. Sánchez-Vizcaíno, Jose M. Sánchez-Vizcaíno, Jose A. Barasona, Jose A. Barasona   +16 more
doaj   +2 more sources