Results 81 to 90 of about 1,396,897 (310)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Demands for real and financial assets in Botswana [PDF]
Traditionally, asset demands are derived as a solution to the individual's or household's problem of allocating wealth among various real and financial alternatives.
Dee, Philippa S.
core
Demands for real and financial assets in Botswana [PDF]
Traditionally, asset demands are derived as a solution to the individual's or household's problem of allocating wealth among various real and financial alternatives.
Dee, Philippa S.
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A dynamic singular equation system of asset demand [PDF]
The paper presents estimates of a dynamic demand system of the AIDS type for financial assets. The results suggest that dynamic behavior plays a major role in determining asset demand.
Weichert, Ronald, Zietz, Joachim
core
Envelopes of Vector Random Processes and Their Crossing Rates
Vector-valued random processes, $\mathbf{X}(t)$, can be "enveloped" by set-valued random processes, $\mathscr{S}(t)$, to which they belong with probability 1 during any finite length of time. When applied to scalar processes, the set-definition of envelope includes and is richer than the familiar point-definitions. Several random set-envelope processes
openaire +2 more sources
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Real-Time Anomaly Detection using Average Level-Crossing Rate
Vibration data collected from piezoelectric sensors serve as a means for detecting faults in machines that have rotating parts. The sensor output that is sampled at the Nyquist rate is stored for analysis of faults in the traditional condition monitoring system. The massive amount of data makes the analysis very difficult.
Premanand B*, V. S. Sheeba
openaire +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Susan Nantume,1 Eric Murungi Baluku,2 Doris Kwesiga,1 Peter Waiswa1 1College of Health Science, Makerere University, Kampala, Uganda; 2Department of Nursing, Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, UgandaCorrespondence:
Nantume S +3 more
doaj

