Results 51 to 60 of about 4,416,441 (310)

Linking cross-reactivity clusters of food and respiratory allergens in PAMD@ to asthma and duration of allergy

World Allergy Organization Journal, 2020
Background: Component resolved diagnosis, recently redefined as precision allergy medicine diagnosis — PAMD@, may help understanding allergic cross-reactivity patterns among polysensitized patients and their clinical implication.
Shadan Ghandizadeh Dezfouli, Nadine Mothes-Luksch, Annika N. Jensen, Eva Untersmayr, Michael Kundi, Erika Jensen-Jarolim   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Shigella sonnei and Shigella flexneri: Epidemiology supporting development of cross-protective vaccines

Human Vaccines & Immunotherapeutics
Shigellosis represents a major global health challenge, significantly contributing to mortality among children under five, particularly in sub-Saharan Africa and South Asia. Advances in molecular techniques have underscored the extensive global impact of
Valentina Caradonna, Agnes Hunyady, Usman Nakakana, Miren Iturriza, Francesca Micoli, Omar Rossi, Francesca Mancini   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Cross family christmas card, 1954 [picture] : "merry xmas and a happy new year to from stan cross and his family december 1954" /

, 1954
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Two copies of original drawing. "Merry Xmas and a Happy New Year From Stan Cross and his Family December 1954"; Also available in an electronic version via the internet at: http://nla ...
Cross, Stan, 1888-1977.
core   +2 more sources

Identification of candidate antigens from adult stages of Toxocara canis for the serodiagnosis of human toxocariasis

Memorias do Instituto Oswaldo Cruz, 2011
In the present work, we identified adult Toxocara canis antigens through sodium dodecyl sulfate-polyacrylamide gel electrophoresis for potential use in human toxocariasis immunodiagnosis. The sensitivity and specificity of several semi-purified antigens,
Patrícia Longuinhos Peixoto, Evaldo Nascimento, Guilherme Grossi Lopes Cançado, Rodrigo Rodrigues Cambraia de Miranda, Regina Lunardi Rocha, Ricardo Nascimento Araújo, Ricardo Toshio Fujiwara   +6 more
doaj   +1 more source

Immunological Cross-Reactivity between Malaria Vaccine Target Antigen P48/45 in Plasmodium vivax and P. falciparum and Cross-Boosting of Immune Responses. [PDF]

PLoS ONE, 2016
In general, malaria immunity has been suggested to be species specific with very little, if any, known cross-reactivity between Plasmodium vivax and P. falciparum, both of which are responsible for >90% of human malaria, and co-endemic in many countries.
Yi Cao, Geetha P Bansal, Kristen Merino, Nirbhay Kumar   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The Influence of Cross-Reactive T Cells in COVID-19

Biomedicines
Memory T cells form from the adaptive immune response to historic infections or vaccinations. Some memory T cells have the potential to recognise unrelated pathogens like severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and generate cross ...
Peter J. Eggenhuizen, Joshua D. Ooi
doaj   +1 more source