Results 91 to 100 of about 8,215,454 (316)
The Crop Ontology (CO) of the Generation Challenge Program (GCP) (http://cropontology.org/ ) is developed for the Integrated Breeding Platform (https://www.integratedbreeding.net/ ) by several centers of The Consultative Group on International ...
Rosemary eShrestha +6 more
doaj +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
When referring to an object in relation to another, speakers of many languages can adopt a relative frame of reference (FoR). Following Levinson (2003), this kind of FoR can be established by projecting an observer’s perspective onto the ground object ...
Sieghard eBeller +3 more
doaj +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Is Inuktitut a morphological argument language? [PDF]
In the following I will discuss grammatical structures of Inuktitut, an Eskimo language spoken in the Canadian Eastern Arctic. Inuktitut is a polysynthetic language exhibiting an exceedingly elaborate verbal inflectional system including polypersonal ...
Nowak, Elke
core
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Wikis supporting authentic, collaborative activities: lessons in usability [PDF]
The Open University delivers distance learning to its students. Traditionally, its students work independently of each other. Looking to enhance their students learning, two postgraduate courses have introduced authentic, collaborative activities.
King, David +3 more
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Cross-Referencing Self-Training Network for Sound Event Detection in Audio Mixtures. [PDF]
Park S, Han DK, Elhilali M.
europepmc +1 more source

