Results 81 to 90 of about 8,215,454 (316)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Skylab-2 handheld photography alphabetized geographical features list [PDF]

open access: yes
This publication represents a relisting of the Skylab-2, PTD Handheld Photography Catalog. The purpose of this publication is to provide imagery researchers a supplement to the PTD Catalog by alphabetically sorting together all similar major and minor ...
Devalcourt, C. C., Mcniel, J. L.
core   +1 more source

Spitzer 24-micron Time-Series Observations of the Eclipsing M-dwarf Binary GU Bootis

open access: yes, 2007
We present a set of {\it Spitzer} 24$\mu$m MIPS time series observations of the M-dwarf eclipsing binary star GU Bo\"otis. Our data cover three secondary eclipses of the system: two consecutive events and an additional eclipse six weeks later.
Claret A.   +8 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Mais qu’est-ce qui se passe dans le coin lecture ?

open access: yesRepères, 2017
This article aims to explore the use of the reading corners in a wide sample of first year classes in primary schools. It forms part of the following educational trend: the teaching of writing with an emphasis on the development of the “reader subject ...
Catherine Frier, Anne Vadcar
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

On issues of labelling in the dictionnaire Français–Mpongwé : a case-study [PDF]

open access: yes, 2009
Dictionaries contain lexicographic data whose occurrence is restricted to certain geo-graphical areas, subject fields, professions, etc. It is part of the duties of the lexicographer to give an account of such deviations to ensure a successful retrieval ...
Mavoungou, Paul Achille
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

THE ROLE OF QUALITY: SPANISH WOOL IN PORTUGUESE TRADE IN THE EARLY NINETEENTH CENTURY

open access: yesEssays in Economic and Business History, 2007
Cross-referencing qualitative and quantitative statistics from handwritten Portuguese trade sources shows the Spanish in the first half of the 19th century using Portuguese trade to introduce their wool in English and other markets.
Maria Moreira
doaj   +2 more sources

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