Results 61 to 70 of about 8,215,454 (316)

Co‐operative cross‐platform courseware development [PDF]

open access: yes, 1996
The UKMCC (UK Mathematics Courseware Consortium) is a Consortium funded under TLTP (Training and Learning Technology Programme) to produce courseware for service mathematics teaching, using the SEFI (Société Européenne pour la Formation des Ingénieurs ...
Harding, R. D., Lay, S. W., Moule, H.
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Evaluation of spa-typing of methicillin-resistant Staphylococcus aureus using high-resolution melting analysis

open access: yesInternational Journal of Infectious Diseases, 2015
Objective: spa-typing of methicillin-resistant Staphylococcus aureus (MRSA) has been used widely in clinical diagnostics and epidemiological studies. The aim of this study was to evaluate high-resolution melting (HRM) as a rapid and cost-effective method,
Waleed Mazi   +4 more
doaj   +1 more source

Towards two-stage service representation and reasoning: from lightweight annotations to comprehensive semantics [PDF]

open access: yes, 2010
Semantics are used to mark up a wide variety of data-centric Web resources but are not used to annotate online functionality in significant numbers. That is despite considerable research dedicated to Semantic Web Services (SWS).
Benn, Neil   +6 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Identifiers.org/MIRIAM Registry annotation and cross-referencing framework [PDF]

open access: yesNature Precedings, 2011
AbstractWe describe the MIRIAM Registry, which forms a foundation layer database upon which persistent, unambiguous and perennial identifiers of data can be built. We describe the existing MIRIAM URI identifiers, and the newly minted resolvable, parallel forms of these identifiers which use Identifiers.org URLs.
Nick Juty   +3 more
openaire   +2 more sources

The (un)happiness of knowledge and the knowledge of (un)happiness: Happiness research and policies for knowledge-based economies [PDF]

open access: yes, 2008
Paper presented to the International Conference Policies for Happiness, June 14-17, 2007, Certosa di Pontignano, University of Siena, Italy.This paper explores the current state and interfaces of two broad policy discourses, i.e.
Engelbrecht, Hans-Juergen
core   +1 more source

Bible Software

open access: yes, 2007
This article is a statement of unbridled praise for the present state of software available for Bible studies, particularly in the use of the Biblical text in its original languages and alphabets.
Bain, Michael
core   +1 more source

A Molecular Biology Database Digest [PDF]

open access: yes, 2000
Computational Biology or Bioinformatics has been defined as the application of mathematical and Computer Science methods to solving problems in Molecular Biology that require large scale data, computation, and analysis [18].
Bry, François, Kröger, Peer
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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