Results 61 to 70 of about 942,688 (340)

Drug-related mutational patterns in hepatitis B virus (HBV) reverse transcriptase proteins from Iranian treatment-Naïve chronic HBV patients [PDF]

, 2013
Background: Immunomodulators and Nucleotide analogues have been used globally for the dealing of chronic hepatitis B virus (HBV) infection. However, the development of drug resistance is a major limitation to their long-term effectiveness.
Abedi, F., Alavian, S.M., Ataei, B., Azad, T.M., Daram, M., Fazeli, Z., Ghamari, S., Goodarzi, Z., Jazayeri, S.M., Judaki, M.A., Kalantari, E., Karimzadeh, H., Keyvani, H., Khedive, A., Mahabadi, M., Mahmoodi, M., Malekzadeh, R., Mansour-Ghanaei, F., Montazeri, G., Moradi, A., Nejatizadeh, A., Norouzi, M., Pourhosseingholi, M.A., Rafatpanah, H., Ramezani, F., Saberfar, E., Saberfiroozi, M., Samimirad, K., Sanei-Moghaddam, I., Sarizadeh, G., Sayad, B., Somi, M.H., Yaran, M., Ziee, M.   +33 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

First Report on Assessing the Severity of Herbicide Resistance to ACCase Inhibitors Pinoxaden, Propaquizafop and Cycloxydim in Six Avena fatua Populations in Ireland

Agronomy, 2020
In response to growers reports of poor weed control, resistance to ACCase inhibitors pinoxaden, propaquizafop and cycloxydim was investigated in populations of six wild oats, Avena fatua, collected from cereal-dominated crop rotations in Ireland ...
Vijaya Bhaskar Alwarnaidu Vijayarajan, Patrick D. Forristal, Sarah K. Cook, Jimmy Staples, David Schilder, Michael Hennessy, Susanne Barth   +6 more
doaj   +1 more source

The Different Response to an Acid Shock of Two Salmonella Strains Marks Their Resistance to Thermal Treatments

Frontiers in Microbiology, 2021
Microbial cells respond to sub-lethal stresses with several physiological changes to increase their chance of survival. These changes are of high relevance when combined treatments (hurdle technology) are applied during food production, as the cells ...
Marta Clemente-Carazo, José-Juan Leal, Juan-Pablo Huertas, Alberto Garre, Alfredo Palop, Paula M. Periago   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Shifting sensitivity of septoria tritici blotch compromises field performance and yield of main fungicides in Europe

Frontiers in Plant Science, 2022
Septoria tritici blotch (STB; Zymoseptoria tritici) is a severe leaf disease on wheat in Northern Europe. Fungicide resistance in the populations of Z. tritici is increasingly challenging future control options.
Lise Nistrup Jørgensen, Niels Matzen, Thies Marten Heick, Aoife O’Driscoll, Bill Clark, Katherine Waite, Jonathan Blake, Mariola Glazek, Claude Maumene, Gilles Couleaud, Bernd Rodemann, Stephan Weigand, Charlotte Bataille, Bán R, Pierre Hellin, Steven Kildea, Gerd Stammler   +16 more
doaj   +1 more source

Acaricide resistance and genetic affinities of some selected populations of Tetranychus urticae Koch in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science (Horticultural) in Entomology at Massey University [PDF]

, 1973
A study of resistance to acaricides in a number of populations of the two-spotted spider mite, Tetranychus urticae, in New Zealand had been carried out.
Ong, S. H.
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Toxicity and binding analyses of Bacillus thuringiensis toxin Vip3A in Cry1Ac-resistant and -susceptible strains of Helicoverpa armigera (Hübner)

Journal of Integrative Agriculture, 2015
The Bacillus thuringiensis vegetative insecticidal protein, Vip3A, represents a new family of Bt toxin and is currently applied to commercial transgenic cotton.
Qian ZHANG, Li-zhen CHEN, Qiong LU, Yan ZHANG, Ge-mei LIANG   +4 more
doaj   +1 more source