Results 51 to 60 of about 17,263,696 (263)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The bending stiffness of pulp fibers in both dry and wet states is of great importance with respect to many optical and physical paper properties. We introduce a method that evaluates fiber bending stiffness from the fibers’ Young’s modulus (E) and the ...
Christian Lorbach +4 more
doaj +1 more source
Wally and the Major [picture] : cross purposes /
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 8/47"--Lower right. "5496 Mon Mar 10 Cross Purposes"--In ink, right margin; "5419"--In ink, upper right corner; "11"--In pencil, upper left corner.; Also ...
Cross, Stan, 1888-1977.
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
In order to study the spatial breakup characteristics of the initial section of low-pressure jets, an experiment was performed to investigate the flow fields and concentration fields of jet flows with different nozzle geometric parameters and also the ...
Yue Jiang +3 more
doaj +1 more source
Wally and the Major [picture] : cross purposes /
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 8/195"--In ink, lower right. "8757 Fri Aug 16 Cross Purposes"--In ink, right margin; "8757"--In pencil, upper right corner; "6"--In pencil, upper left corner ...
Cross, Stan, 1888-1977.
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Using Deep Learning and B-Splines to Model Blood Vessel Lumen from 3D Images
Accurate geometric modeling of blood vessel lumen from 3D images is crucial for vessel quantification as part of the diagnosis, treatment, and monitoring of vascular diseases.
Andrzej Materka, Jakub Jurek
doaj +1 more source
Wally and the Major [picture] : cross purposes /
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross 9/66"--In ink, lower right. "8939 Tue Mar 18 Cross Purposes"--In ink, right margin; "8939"--In pencil, upper right corner.; Also available in an electronic ...
Cross, Stan, 1888-1977.
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source

