Results 121 to 130 of about 4,771,637 (376)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Epidemiological profile of patients treated at the Cornea's Department of the Reference Center in Ophthalmology, Goiás, Brazil [PDF]

Revista Brasileira de Oftalmologia
Objective: To describe the epidemiological profile of corneal disorders diagnosed in the Corneal Department of the Ophthalmology Reference Center, Universidade Federal de Goiás, between 2009 and 2018.
Fernanda Mendonça Galvão, Alexia Larissa de Souza, Hugo Mendes Silva, Marcia Cristina Toledo, Victor Falcão Pereira Costa, Yael Porto Silva, Cláudia Gomide Vilela de Sousa Franco, Larissa Fernanda Queiroz Elias, Marcos Rassi Fernandes   +8 more
doaj   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Hepatitis-C Virus Infection among Injecting Drug Users in Lahore, Pakistan: A Descriptive and Analytical Cross Sectional Study [PDF]

, 1969
Abdul Majeed Akhtar, Sadia Majeed, Muhammad Jamil, Abdul Rehman, Sufia Majeed   +4 more
openalex   +1 more source

A systematic review of the association between circulating concentrations of C reactive protein and cancer.

, 2007
The objective of this study was to review and summarise the published evidence for an association between circulating concentrations of C reactive protein (CRP) and cancer through a systematic review. 90 discrete studies were identified.
Ebrahim, Shah, Heikkilä, Katriina, Lawlor, Debbie A   +2 more
core   +1 more source

Effects of channel cross-sectional geometry on long wave generation and propagation [PDF]

, 1997
Joint theoretical and experimental studies are carried out to investigate the effects of channel cross-sectional geometry on long wave generation and propagation in uniform shallow water channels. The existing channel Boussinesq and channel KdV equations
Teng, Michelle H., Wu, Theodore Y.
core   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

STROCSS 2021: Strengthening the reporting of cohort, cross-sectional and case-control studies in surgery

Annals of Medicine and Surgery, 2021
R. Agha, Ginimol Mathew, J. Albrecht, P. Goel, I. Mukherjee, P. Pai, A. D'cruz, I. Nixon, Klappenbach Roberto, S. Enam, S. Basu, O. Muensterer, S. Giordano, D. Pagano, D. Machado-Aranda, P. Bradley, M. Bashashati, A. Thoma, R. Afifi, M. Johnston, B. Challacombe, J. Ngu, Mushtaq Chalkoo, K. Raveendran, J. Hoffman, B. Kirshtein, W. Lau, M. Thorat, D. Miguel, A. Beamish, Gaurav Roy, D. Healy, M. Ather, S. Raja, Z. Mei, T. Manning, V. Kasivisvanathan, J. Rivas, R. Coppola, B. Ekser, Veena L. Karanth, H. Kadioglu, Michele Valmasoni, A. Noureldin   +43 more
semanticscholar   +1 more source