Results 91 to 100 of about 3,642,371 (354)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Phonological recoding in error detection: a cross-sectional study in beginning readers of Dutch [PDF]

, 2012
The present cross-sectional study investigated the development of phonological recoding in beginning readers of Dutch, using a proofreading task with pseudohomophones and control misspellings.
Duyck, Wouter, Hartsuiker, Robert, Van Assche, Eva   +2 more
core   +4 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

IJCM_24A: Determinants of unintended pregnancy among women attending Antenatal clinic at AIIMS Patna – a cross-sectional study

Indian Journal of Community Medicine
Background: Every day 67,385 babies are born in India, that’s around one- sixth of the world’s childbirths. Every minute one of these new-borns dies, with an annual birth rate of 25 million which accounts for nearly one-fifth of the world’s annual ...
Roy Parvati, Ahmad Shamshad, Kumar Pragya   +2 more
doaj   +1 more source

Perfectionism and training distress in junior athletes: A longitudinal investigation [PDF]

, 2016
Perfectionistic athletes may train harder and for longer than non-perfectionistic athletes, leaving them susceptible to elevated levels of training distress.
Antony M. M., Daniel J. Madigan, Flett G. L., Hill A. P., Joachim Stoeber, Louis Passfield, McNair D. M., Raglin J. S., Raglin J. S., Stoeber J., Tabachnick B. G.   +10 more
core   +2 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Association of overactive bladder with red cell distribution width to albumin ratio in American

Scientific Reports
Overactive bladder (OAB) significantly affects places a considerable economic strain and individuals’ quality of life on global healthcare resources.The ratio of red cell distribution width to albumin (RAR) is a novel inflammatory marker, yet its ...
Kun Zhou, Zehui Rao, ingyu Chen, Zhen Guo, Jun Luo, Yida Zhang   +5 more
doaj   +1 more source

Distinct aspects of pain catastrophizing according to chronic pain syndromes

Clinical and Biomedical Research, 2018
Introduction: Catastrophizing is the tendency to magnify the threat value of pain and has been associated with measures of physical and psychological disability among individuals with several pain conditions.
Maxciel Zortea, Luciana da Conceição Antunes, Joice Dickel Segabinazi, Gerardo Beltran Serrano, Jéssica Lorenzzi Elkfury, Fabiana Carvalho, Vinicius Souza Santos, Wolnei Caumo   +7 more
doaj   +2 more sources

HIV screening among newly diagnosed TB patients : a cross sectional study in Lima, Peru [PDF]

, 2018
Background: Since 2006, the Peruvian National TB program (NTP) recommends voluntary counseling and testing (VCT) for all tuberculosis (TB) patients.
Gotuzzo, Eduardo, Mejia, Fernando, Otero, Larissa, Ramirez, Suzanne, Rojas, Marlene, Seas, Carlos, Van Der Stuyft, Patrick   +6 more
core   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source