Results 71 to 80 of about 3,642,371 (354)
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
A Study of Depression Among Aged in Surat City
National Journal of Community Medicine, 2010 This cross-sectional study interviews 105 elderly belonging to different socioeconomic and varying demographic groups of Surat city as per predefined inclusion and exclusion criteria with their informed consent in compliance with 'Ethical principles for
Vishal Jariwala +3 more
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BMC Research Notes, 2011 Background In oral implantology, there is no consensus on the most appropriate regimen for antibiotics prescribing, the decision to prescribe antibiotic is usually based on procedure, patient and clinician related factors.
Hamdan Ahmad AS +7 more
doaj +1 more source
Experiences of cancer rehabilitation: A cross‐sectional study [PDF]
Journal of Clinical Nursing, 2018 Aims and objectivesTo investigate the cancer rehabilitation experiences of working‐age cancer survivors.BackgroundCancer survivors have extremely complex needs, spanning physical, vocational and sexual domains. Although cancer rehabilitation services have been found to eliminate or reduce these strains, these services are often underutilised.DesignA ...
Pernilla Garmy +2 more
openaire +5 more sources
Paediatric malaria case-management with Artemether-Lumefantrine in Zambia: a repeat cross-sectional study [PDF]
, 2007 BACKGROUND Zambia was the first African country to change national antimalarial treatment policy to artemisinin-based combination therapy – artemether-lumefantrine.
Dejan Zurovac +36 more
core +9 more sources
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Periodontitis in patients with cirrhosis: a cross-sectional study [PDF]
BMC Oral Health, 2018 Many patients with cirrhosis have poor oral health but little is known on periodontitis, and its clinical significance is largely unknown. This study aimed to examine the prevalence and predictors of periodontitis, and evaluate the association of periodontitis with nutritional and systemic inflammation status.145 patients with cirrhosis were ...
Grønkjær, Lea Ladegaard +5 more
openaire +7 more sources
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Prevalence of obesity and overweight in primary school girls in Tehran, Iran
Payesh, 2002 Objective(s): The rising trends of obesity in children are reflected in increased adult obesity and related morbidity. So we studied the prevalence of obesity in children and the related factors in Tehran.
Mozafary H, Nabaie B
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