Results 91 to 100 of about 1,297,248 (245)
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Electron Capture Cross Sections for Stellar Nucleosynthesis
In the first stage of this work, we perform detailed calculations for the cross sections of the electron capture on nuclei under laboratory conditions.
P. G. Giannaka, T. S. Kosmas
doaj +1 more source
Measurement of Hadronic Cross Sections at BESIII
The uncertainties of the Standard Model prediction of the anomalous magnetic moment of the muon are currently completely dominated by hadronic contributions. The largest contribution is due to the hadronic vacuum polarization.
Redmer, C. F.
core +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Photoionization of Trans-Fe Ions: Se IV, Se V, and Se VI
In the present study, the photoionization cross-sections are calculated for the trans-Fe ions Se IV, Se V, and Se VI over a wide energy region for ground and meta-stable states within the Dirac Atomic R-matrix approach (darc).
Brendan M. McLaughlin +2 more
doaj +1 more source
Tables of nuclear cross sections for galactic cosmic rays: Absorption cross sections [PDF]
A simple but comprehensive theory of nuclear reactions is presented. Extensive tables of nucleon, deuteron, and heavy-ion absorption cross sections over a broad range of energies are generated for use in cosmic ray shielding studies. Numerous comparisons
Townsend, L. W., Wilson, J. W.
core +1 more source
Multiple-electron losses of highly charged ions colliding with neutral atoms
We present calculations of the total and m-fold electron-loss cross sections using the DEPOSIT code for highly charged U(q+) ions (q=10,31,33) colliding with Ne and Ar targets at projectile energies E=1.4 and 3.5 MeV/u.
M S Litsarev +5 more
core +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Cyclohexane Vibronic States: A Combined VUV Spectroscopy and Theoretical Study
In this work, we provide results from a joint experimental and theoretical study of the vibronic features of cyclohexane (C6H12) in the photon energy range of 6.8–10.8 eV (182–115 nm).
Edvaldo Bandeira +5 more
doaj +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source

