Results 201 to 210 of about 1,327,683 (276)

Global research trends in metabolism-related intraocular malignancies: a multi-database bibliometric analysis and cross-validation study. [PDF]

Front Mol Biosci
Bai J, Wan Z, Wu Z, Peng Q.
europepmc   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Cross-validation of an artificial intelligence tool for fracture classification and localization on conventional radiography in Dutch population. [PDF]

Insights Imaging
Ruitenbeek HC, Sahil S, Kumar A, Kushawaha RK, Tanamala S, Sathyamurthy S, Agrawal R, Chattoraj S, Paramasamy J, Bos D, Fahimi R, Oei EHG, Visser JJ.   +12 more
europepmc   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Development and internal-external cross-validation of a patient-reported definition for acute calcium pyrophosphate crystal arthritis. [PDF]

Rheumatology (Oxford)
Cipolletta E, Rozza D, Andres M, Ottaviani S, Pascart T, Calvo-Aranda E, Chiarvetto Peralta MV, Muto P, Calabuig I, Gómez-Sabater S, Caño R, Léger B, Pacaud A, Moscioni E, Bruno C, Caira V, Gómez-González C, Rosa JE, Nakafero G, Filippucci E, Abhishek A.   +20 more
europepmc   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Development and cross-validation of a novel multi-omic assay to assess locoregional recurrence risk and adjuvant therapy benefit in early-stage hormone receptor positive invasive breast cancer patients. [PDF]

Breast Cancer Res
Bremer T, Mittal K, Shah C, Vicini F, Gerber NK, Krystel-Whittemore M, Yates CC, Karanam B, Bell W, Borak SG, Cox CE, Beard A, Acs G, Reid V, Al-Hilli Z, Shivers SC, Mentrikoski M, Dabbs D, Savala J, Whitworth PW, Wadsten C.   +20 more
europepmc   +1 more source