Results 41 to 50 of about 4,483,884 (302)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Short-Term Exuberance and Long-Term Stability: A Simultaneous Optimization of Stock Return Predictions for Short and Long Horizons

Mathematics, 2021
The fundamental interest of investors in econometric modeling for excess stock returns usually focuses either on short- or long-term predictions to individually reduce the investment risk.
Ioannis Kyriakou, Parastoo Mousavi, Jens Perch Nielsen, Michael Scholz   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Exploratory data analysis in the context of data mining and resampling.

International Journal of Psychological Research, 2010
Today there are quite a few widespread misconceptions of exploratory data analysis (EDA). One of these misperceptions is that EDA is said to be opposed to statistical modeling.
Chong Ho Yu
doaj   +1 more source

Accuracy Evaluation of the FY-4A AGRI Land Surface Temperature Product

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2023
Land surface temperature (LST) plays a key role in surface-atmosphere interactions and energy exchange processes and is an important parameter indispensable for earth science research. The LST accuracy retrieved from the Advanced Geosynchronous Radiation
Yiyao Gao, Shanyou Zhu, Guixin Zhang, Yongming Xu   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A Failed Cross-Validation Study on the Relationship between LIWC Linguistic Indicators and Personality: Exemplifying the Lack of Generalizability of Exploratory Studies

Psych, 2022
(1) Background: Previous meta-analytic research found small to moderate relationships between the Big Five personality traits and different linguistic computational indicators.
José Ángel Martínez-Huertas, José David Moreno, Ricardo Olmos, Alejandro Martínez-Mingo, Guillermo Jorge-Botana   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

MHAU-Net: Skin Lesion Segmentation Based on Multi-Scale Hybrid Residual Attention Network

Sensors, 2022
Melanoma is a main factor that leads to skin cancer, and early diagnosis and treatment can significantly reduce the mortality of patients. Skin lesion boundary segmentation is a key to accurately localizing a lesion in dermoscopic images.
Yingjie Li, Chao Xu, Jubao Han, Ziheng An, Deyu Wang, Haichao Ma, Chuanxu Liu   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source