Results 31 to 40 of about 5,168,827 (263)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Cross family christmas card, 1957 [picture] : "greetings at christmas 1957 From stan and jess cross and stephen" /

open access: yes, 1957
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Copy of original drawing. "Greetings at Christmas 1957 From Stan and Jess Cross and Stephen"; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic ...
Cross, Stan, 1888-1977.
core   +2 more sources

Grasping Claws of Bionic Climbing Robot for Rough Wall Surface: Modeling and Analysis

open access: yesApplied Sciences, 2017
Aiming at the inspection of rough stone and concrete wall surfaces, a grasping module of cross-arranged claw is designed. It can attach onto rough wall surfaces by hooking or grasping walls.
Quansheng Jiang, Fengyu Xu
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Diagnostic ability of limited volume cone beam computed tomography with small voxel size in identifying the superior and inferior walls of the mandibular canal

open access: yesInternational Journal of Implant Dentistry, 2018
Background The aim of this study was to evaluate the visibility of the superior and inferior walls of the mandibular canal separately using limited volume cone beam computed tomography (CBCT) with small voxel size.
Hiroko Ishii   +5 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Associations Between Hemodynamics, Shape and Atherosclerosis in M1 of Middle Cerebral Artery: Insights From 4‐Dimensional Flow Magnetic Resonance Imaging in Patients With Ischemic Stroke

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Intracranial atherosclerosis is a major cause of ischemic stroke. Vascular shape affects hemodynamics and plaque development. This study aims to investigate the relationships among M1 shape, hemodynamics, plaque distribution, and stroke ...
Lixin Liu   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Experimental and Numerical Analyses of New Massive Wooden Shear-Wall Systems

open access: yesBuildings, 2014
Three innovative massive wooden shear-wall systems (Cross-Laminated-Glued Wall, Cross-Laminated-Stapled Wall, Layered Wall with dovetail inserts) were tested and their structural behaviour under seismic action was assessed with numerical simulations. The
Luca Pozza   +5 more
doaj   +1 more source

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