Results 91 to 100 of about 3,249,205 (265)

Pain and meaning - religious interpretations of pain Christian metamorphoses [PDF]

Temida
The early Christian understanding of pain was shaped by faith in Jesus Christ as the deliverer from death, pain, and suffering, which is also evident in early Christian symbolism and iconography.
Milićević Vukašin
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Modeling of Six Openers for Seeding Machines, Cross-Shaped, T-Inverse, U-Shaped, V-Shaped, V-Shaped with Two Plates and Tulip-Shaped [PDF]

Biomechanism and Bioenergy Research
The use of cultivation techniques that can properly prepare the seed bed and plant the seeds at an almost uniform depth has become necessary more than ever. In this research, the plane sitting test was used for modeling.
Behnam Sepehr, isa Hazbawi
doaj   +1 more source

Portrait of Jessie Cross, Stan's wife, ca. 1920 [picture] /

, 1920
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Jessie Cross Stan's wife"--In ink, on verso.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic ...
Cross, Stan, 1888-1977.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Things that make Stan cross [picture] : what makes inflation? /

, 1900
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross"--In ink, lower right. "Page 5"--In ink, on note attached to verso.; Title devised by cataloguer.; Also available in an electronic version via the internet at ...
Cross, Stan, 1888-1977.
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

La Croix et son Lieu consacré dans l'église, une lecture mystagogique de l'espace ecclésial / The Cross and its Consecrated Place in the Church, a Mystagogic Reading of Ecclesial Space [PDF]

Anastasis: Research in Medieval Culture and Art, 2015
This paper discusses the place of the cross in ecclesial spaces in context of western medieval Christendom based on the study of the three liturgical arrangements: the pergula/templon, the altar of the Cross and the trabs doxalis.
Clémence Figeac
doaj