Results 121 to 130 of about 13,884,348 (293)

Space bioreactor: Design/process flow [PDF]

open access: yes
The design of the space bioreactor stems from three considerations. First, and foremost, it must sustain cells in microgravity. Closely related is the ability to take advantage of the weightlessness and microgravity.
Cross, John H.
core   +1 more source

The Delinquency of Subprime Mortgages [PDF]

open access: yes, 2007
The lag between the time that a borrower stops making payments on a mortgage and the termination of the loan plays a critical role in the costs borne by both borrower and lender on defaulted loans.
Danis, Michelle A   +1 more
core   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Alternative Methods of Increasing the Precision of Weighted Repeat Sales House Prices Indices* [PDF]

open access: yes, 2004
Weighted repeat sales house price indices have become one of the primary indicators used to identify housing market conditions and to estimate the amount of equity homeowners have gained through house price appreciation.
Dreiman, Michelle H   +1 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Pattern formation of quantum jumps with Rydberg atoms [PDF]

open access: yes, 2012
We study the nonequilibrium dynamics of quantum jumps in a one-dimensional chain of atoms. Each atom is driven on a strong transition to a short-lived state and on a weak transition to a metastable state.
Cross, Michael C., Lee, Tony E.
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

The challenges and potential benefits of perennial organic cropping systems-example of organic top fruit [PDF]

open access: yes, 2006
Of all the organic food sectors in the UK, top fruit production is one of the least developed. Despite strong consumer demand and high prices for organic fruit, UK production remains small and 90% of supplies are imported.
Cross, J, Cubison, S, Firth, C
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Laboratory investigations: Low Earth orbit environment chemistry with spacecraft surfaces [PDF]

open access: yes
Long-term space operations that require exposure of material to the low earth orbit (LEO) environment must take into account the effects of this highly oxidative atmosphere on material properties and the possible contamination of the spacecraft ...
Cross, Jon B.
core   +1 more source

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