Results 91 to 100 of about 251,458 (268)
Complex monitoring of the sports training level depending on dietary lipids
ACROSSThe essential components of food are proteins, fats and fuels. In this paper, we will analyze one of the main macronutrients: fats, also called lipids. First, dietary lipids are indeed exceptional sources of energy.
Veaceslav MANOLACHI
doaj +1 more source
Cross-border co-operation as policy entrepreneurship: explaining the variable success of European cross-border regions [PDF]
, 2005 The article addresses the recent proliferation of Cross-Border Regions, or Euroregions, across the EU. It aims to explain why they have been more successfully institutionalised in some areas while they have had less success in others.
Perkmann, Markus
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
PathogensChicken parvovirus (ChPV) infection can cause runting-stunting syndrome (RSS) in chickens. There is currently no commercially available vaccine for controlling ChPV, and ChPV infection in chickens is widespread globally.
Minxiu Zhang +10 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Scientific ReportsAn enzyme-free sandwich amperometric immunosensor based on bimetallic Pt/Ag nanoparticle (Pt/AgNPs)-functionalized chitosan (Chi)-modified multiwalled carbon nanotubes (MWCNTs) as dual signal amplifiers and Chi-modified MWCNTs (MWCNTs-Chi) as substrate ...
Jiaoling Huang +15 more
doaj +1 more source
Cross-Border Work in Europe. Realities and Challenges
Living in one country and working in another is a daily reality for thousands of people in Europe. The contributions in this book analyze the many facets of cross-border worker flows, identifying similarities and differences from one area to another. The
Belkacem, Rachid +2 more
core
Making Cross Border Enforcement More Effective for Creditors
, 2021 peer reviewedThe European Union has worked at making cross-border enforcement more effective for more than 50 years. The process initially focused on the circulation of foreign judgments rendered in civil and commercial matters within the European ...
CUNIBERTI, Gilles
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source