Results 121 to 130 of about 1,105,274 (313)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Comparisons of Membrane Fouling and Separation Efficiency in Protein/Polysaccharide Cross-Flow Microfiltration using Membranes with Different Morphologies

open access: yes, 2014
The membrane fouling and filtration performance of Bovine serum albumin (BSA)/dextran cross-flow microfiltration using membranes with different morphologies are analyzed and compared. Three 0.1 μm hydrophilic membranes made of mixed cellulose ester (MCE),
Hwang, Kuo-Jen   +1 more
core   +1 more source

Compressible material flow in cylindrical channel with variable cross section

open access: yesMATEC Web of Conferences, 2017
In the mathematical model of the flow of compressible material the effect of friction and the slip velocity of the material at the side boundary surfaces are considered.
Pryanishnikova Elena   +2 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Simulation of cross-flow microfiltration by multiphase flow model

open access: yes, 2010
碩士本研究以多相流模式模擬掃流微過濾之濾餅成長情形,探討濾餅的性質與結垢的機制,並進行掃流過濾實驗,取得數據作為比較,並了解掃流微過濾之特性。實驗中使用平均孔徑為0.1 μm的醋酸纖維膜(Mixed cellulose ester)過濾平均粒徑為0.8 μm的聚甲基丙烯酸甲酯(PMMA)粒子。在兩相流動的掃流微過濾中,改變懸浮液濃度與掃流速度,實驗結果顯示,懸浮液濃度越高與掃流速度越慢的條件下濾速越低,平均孔隙度也會逐漸降低。而利用計算流體力學(Computational Fluid Dynamics,
方巽禾; Fang, Hsun-he
core  

Effects of Operating Conditions on the Performance of Cross-Flow Filtration of Viscoelastic Slurry

open access: yes, 2010
The effects of operating conditions, such as rheology of fluid, cross-flow velocity, and filtration pressure, on the cake formation and the performance of cross-flow filtration of viscoelastic slurry are studied.
黃國楨; Hwang, Kuo-jen; Kao, Chien-kuo   +1 more
core   +1 more source

Transparent Cross-Flow Platform as Chemiluminescence Detection Cell in Cross Injection Analysis. [PDF]

open access: yesMolecules, 2023
Somboonsuk T   +6 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Effects of extracellular polymeric substances on the cross-flow microfiltration of bacillus subtilis

open access: yes, 2011
碩士本研究旨在探討枯草桿菌培養液中胞外高分子物質與操作條件對掃流微過濾性能之影響。實驗採用平板式掃流微過濾系統,使用平均孔徑為0.22 μm的聚二氟乙烯(PVDF)濾膜,過濾不同培養天數的枯草桿菌培養液,探討透膜壓差、掃流速度對過濾速度、過濾阻力、蛋白質和多醣體的阻擋率、濾餅性質等之影響。 研究結果發現,培養時間越久的菌體尺寸越大,從培養1天平均尺寸200 μm增加到5天的229 μm;胞外聚合物的濃度亦會隨培養時間而增加,更容易在膜面形成積垢,造成過濾阻力上升。經由過濾阻力分析 ...
蔡明修; Tsai, Ming-Hsiu
core  

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