Results 91 to 100 of about 1,030,546 (307)

Staphylococcal Cross-infection [PDF]

BMJ, 1963
E G, DOLTON, C H, HOWELLS
openaire   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Suppression of Plasmodium falciparum by serum collected from a case of Plasmodium vivax infection [PDF]

, 2008
Background: It has frequently been reported that Plasmodium vivax suppressed Plasmodium falciparum and ameliorated disease severity in patients infected with these two species simultaneously.
Kimura-Sato, M, Chavalitshewinkoon-Petmitr, P, Kimura-Sato Masako, Porntip Chavalitshewinkoon-Petmitr, de Souza, J Brian, Sornchai Looareesuwan, Polrat Wilairatana, Srivicha Krudsood, Tan-Ariya, Peerapan, Thongrungkiat, S, Thongrungkiat, Supatra, Thongrungkiat Supatra, Looareesuwan Sornchai, Peerapan Tan-ariya, Ishida, T, Tan-Ariya, P, Chavalitshewinkoon-Petmitr, Porntip, Krudsood, Srivicha, Ishida Takafumi, Yoshiro Nagao, Masako Kimura-Sato, de Souza, JB, Kimura-Sato, Masako, Tan-ariya Peerapan, Looareesuwan, S, Nagao Yoshiro, Looareesuwan, Sornchai, Nagao, Y, Krudsood, S, Krudsood Srivicha, Chavalitshewinkoon-Petmitr Porntip, de Souza J Brian, Nagao, Yoshiro, Wilairatana Polrat, Takafumi Ishida, Supatra Thongrungkiat, Wilairatana, Polrat, J Brian de Souza, Ishida, Takafumi, Wilairatana, P   +39 more
core   +1 more source

Candida auris, an Emerging Fungal Pathogen

Journal of Mazandaran University of Medical Sciences, 2019
The emerging pathogen “Candida auris” is attracting considerable international attention due to its rising reports, transmission through health professionals, high rate of treatment failure and resistance to multiple antifungal agents, particularly ...
Shahram Mahmoudi, Kazem Ahmadikia, Mohammad Kord, Ali Ahmadi, Sadegh Khodavaisy   +4 more
doaj  

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Mannose-binding lectin 2 polymorphisms do not influence frequency or type of infection in adults with chemotherapy induced neutropaenia. [PDF]

, 2012
BACKGROUND: Mannose-binding Lectin protein (MBL) has been suggested to be relevant in the defence against infections in immunosuppressed individuals.
Öhrmalm, Lars, Michelle Wong, Ohrmalm, L, Öhrmalm L., Lars Öhrmalm, Aust Carl, Tolfvenstam, Thomas, Tolfvenstam T., Hibberd, Martin, Wong, Michelle, Martin Hibberd, Hibberd M., Broliden K., Tolfvenstam, T,, Hibberd, M, Kristina Broliden, Thomas Tolfvenstam, Broliden, K,, Broliden, Kristina, Hibberd Martin, Broliden Kristina, Aust, C,, Wong, M, Carl Aust, Aust C., Wong M., Tolfvenstam Thomas, Öhrmalm Lars, Wong Michelle, Aust, Carl   +29 more
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

A Qualitative and Quantitative Survey on Air-Transmitted Fungal Contamination in Different Wards of Kamkar Hospital in Qom, Iran, in 2007

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2009
Background and Objectives : Fungi spores can be found everywhere. The amount and variety of fungal spores and their vast spread could be a preliminary step to the initiation of different diseases in people with different levels of health.
M Azizifar, H Jabbari, K Naddafi, Nabizadeh, Y Tabaraie, AA Solgi   +5 more
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source