Results 31 to 40 of about 1,509,310 (228)

The use of attenuated isolates of Pepino mosaic virus for cross-protection [PDF]

, 2010
Pepino mosaic virus (PepMV) has recently emerged as a highly infectious viral pathogen in tomato crops. Greenhouse trials were conducted under conditions similar to commercial tomato production.
Hamelink, R., Kaarsemaker, R.C., Schenk, M.F., Stijger, C.C.M.M., Vermunt, A.M.W., Vlugt, R.A.A., van der   +5 more
core   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Spatial mapping and prediction of Plasmodium falciparum infection risk among school-aged children in Côte d'Ivoire [PDF]

, 2016
BACKGROUND: In Côte d'Ivoire, malaria remains a major public health issue, and thus a priority to be tackled. The aim of this study was to identify spatially explicit indicators of Plasmodium falciparum infection among school-aged children and to ...
Assi, Serge-Brice, Chammartin, Frédérique, Fantodji, Agathe, Houngbedji, Clarisse A., Hürlimann, Eveline, Koudou, Benjamin G., N'Dri, Prisca B., N'Goran, Eliézer K., Raso, Giovanna, Silué, Kigbafori D., Soro, Gotianwa, Utzinger, Jürg, Vounatsou, Penelope, Yapi, Richard B.   +13 more
core   +3 more sources

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

Molecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren, Philippe Decruyenaere, Francisco Avila Cobos, Johanna Bult, Jill Deleu, Laudonia Lidia Dipalo, Hetty Hilde Helsmoortel, Eva Hulstaert, Annelien Morlion, Elena Ramos Varas, Kathleen Schoofs, Wim Trypsteen, Eveline Vanden Eynde, Hanne Van Droogenbroeck, Kimberly Verniers, Jo Vandesompele, Anneleen Decock   +16 more
wiley   +1 more source

Horizontal transfer of parasitic sex ratio distorters between crustacean hosts [PDF]

, 1998
Parasitic sex ratio distorters were artificially transferred within and between crustacean host species in order to study the effects of parasitism on host fitness and sex determination and to investigate parasite–host specificity. Implantation of Nosema
Dunn, A.M., Rigaud, T.
core   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

The HIV Genomic Incidence Assay Meets False Recency Rate and Mean Duration of Recency Infection Performance Standards. [PDF]

, 2017
HIV incidence is a primary metric for epidemic surveillance and prevention efficacy assessment. HIV incidence assay performance is evaluated via false recency rate (FRR) and mean duration of recent infection (MDRI).
Anastos, Kathryn, Cohen, Mardge, DeHovitz, Jack, DeHovitz, Jack, Kang, Tina Manzhu, Kober, Kord M, Lee, Ha Youn, Liu, Chenglong, Love, Tanzy MT, Mack, Wendy J, Park, Sung Yong, Reynell, Lucy, Yu, Carl   +12 more
core   +2 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Development of reverse-transcription PCR techniques to analyse the density and sex ratio of gametocytes in genetically diverse Plasmodium chabaudi infections [PDF]

, 2007
We have developed cross-genotype and genotype-specific quantitative reverse-transcription PCR (qRT-PCR) assays to detect and quantify the number of parasites, transmission stages (gametocytes) and male gametocytes in blood stage Plasmodium chabaudi ...
Abdel-Wahab, Alano, Babiker, Bell, Cheeseman, Damien R. Drew, De Roode, De Roode, De Roode, Dye, Ferguson, Ferguson, Foster, Gardner, Gautret, Hamilton, Khan, Mackinnon, Nee, Paterson, Paul, Paul, Paul, Pinheiro, Ranford-Cartwright, Read, Read, Read, Reece, Reece, Reece, Sarah E. Reece, Schall, Schall, Schneider, Shutler, Sinden, Taylor, Taylor, Wargo, Wargo, West, West, West, West   +44 more
core   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source