Results 91 to 100 of about 8,597,124 (379)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Management of Potato virus Y (PVY–NTN) causing PTNRD disease in potato by prior treatment with a mild PVY strain

open access: yesJournal of Plant Protection Research, 2018
Potato virus Y (PVY) is one of the most destructive viruses infecting potato in Egypt and worldwide. Recent research has shown that a necrotic PVY-NTN strain is infecting potato in Upper Egypt.
Osama A. Abdalla   +3 more
doaj   +1 more source

Evolved bacterial siderophore-mediated antibiotic cross-protection

open access: yes, 2023
Abstract Antibiotic cross-protection enables resistant bacteria to protect other bacteria that would be otherwise susceptible to the drug. Cefiderocol is the first siderophore cephalosporin antibiotic approved for treating Gram-negative bacterial infections, including carbapenem-resistant Pseudomonas aeruginosa strains.
Peter Jorth   +6 more
openaire   +2 more sources

Heterosubtypic cross-protection correlates with cross-reactive interferon-gamma-secreting lymphocytes in the ferret model of influenza

open access: yesScientific Reports, 2019
An effective universal vaccine for influenza will likely need to induce virus-specific T-cells, which are the major mediator of heterosubtypic cross-protection between different subtypes of influenza A virus.
K. Gooch   +8 more
semanticscholar   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Credibly Committing to Property Rights: The Roles of Precedent and the Constitution. [PDF]

open access: yes, 2010
In cross-national studies, scholars typically ignore the moderating effect of credibility on the relationship between property rights protection and economic growth.
Melton, James
core  

Protecting paradise: a cross-national analysis of biomeprotection policies [PDF]

open access: yesSustainability: Science, Practice and Policy, 2008
Land protection policies such as creating and preserving national parks have been promoted to counter global threats to the environment and to conserve biodiversity. We know little, however, about the country characteristics that might be good predictors of whether states will choose to protect land or not.
Archer, Candace, Orr, Shannon
openaire   +2 more sources

Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge

open access: yesNature Communications, 2017
Zika virus (ZIKV) and dengue virus (DENV) are antigenically related flaviviruses that share cross-reactivity in antibody and T cell responses, and co-circulate in increasing numbers of countries.
Jinsheng Wen   +6 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy