Results 161 to 170 of about 8,597,124 (379)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Cross-Reactivity, Epitope Spreading, andDe NovoImmune Stimulation Are Possible Mechanisms of Cross-Protection of Nonvaccine Human Papillomavirus (HPV) Types in Recipients of HPV Therapeutic Vaccines [PDF]

, 2015
Mayumi Nakagawa, William W. Greenfield, A. Moerman, Hannah Coleman   +3 more
openalex   +1 more source

Import Protection, Capital Inflows, and Real Exchange Rate Dynamics [PDF]

This paper focuses on the effect of import protection on the response of the real exchange rate to capital flows. The central hypothesis is that barriers to imports blunt the expenditure and production shifting effects of changes in relative prices, and ...
Larry A. Sjaastad, Meher Manzur
core  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Improving the Antigenicity of SARS-CoV-2 Vaccine Genes by Merging Mutations from Different Variants of Concern

Vaccines
During the COVID-19 pandemic, the early emergence of viral variants repeatedly undermined the effects of vaccination. Our aim here is to explore strategies for improving spike vaccine gene antigenicity by merging mutations from different variants of ...
Susanne Herwig, Julia M. Adler, Daria Vladimirova, Jakob Trimpert, Jalid Sehouli, Günter Cichon   +5 more
doaj   +1 more source

Novel Cross-Reactive Monoclonal Antibodies against Ebolavirus Glycoproteins Show Protection in a Murine Challenge Model [PDF]

, 2017
James Duehr, Teddy John Wohlbold, Lisa Oestereich, Veronika Chromikova, Fatima Amanat, Madhusudan Rajendran, Sergio Gómez‐Medina, Ignacio Mena, Benjamin R. tenOever, Adolfo Garcı́a-Sastre, Christopher F. Basler, César Muñoz‐Fontela, Florian Krammer   +12 more
openalex   +1 more source

Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses

, 2022
Syed M. Moin, Jeffrey C. Boyington, Seyhan Boyoglu-Barnum, Rebecca A. Gillespie, Gabriele Cerutti, Crystal Sao‐Fong Cheung, Alberto Cagigi, John R. Gallagher, Joshua Brand, Madhu Prabhakaran, Yaroslav Tsybovsky, Tyler Stephens, Brian E. Fisher, Adrian Creanga, Sila Ataca, Reda Rawi, Kizzmekia S. Corbett, Michelle C. Crank, Gunilla B. Karlsson Hedestam, Jason Gorman, Adrian B. McDermott, Audray K. Harris, Tongqing Zhou, Peter D. Kwong, Lawrence Shapiro, John R. Mascola, Barney S. Graham, Masaru Kanekiyo   +27 more
openalex   +2 more sources

Public and private spending for environmental protection: a cross-country policy analysis [PDF]

OECD data are used to investigate public and private environmental expenditures and, although they are more complete and consistent than other datasets, they are still poor.
Charles Palmer, David Pearce
core  

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

The Dark Side of Shareholder Protection: Cross-country Evidence from Innovation Performance [PDF]

Proponents of minority shareholder protection state that national legal institutions protecting small investors boost stock markets and, in turn, long-term countries’ performance. In this paper, we empirically challenge this argument.
Filippo Belloc
core