Results 61 to 70 of about 625,469 (309)

Aryldiazonium Salts and DABSO: A Versatile Combination for Three‐Component Sulfonylative Cross‐Coupling Reactions [PDF]

, 2022
Pritha Das, Subhodeep Das, Ranjan Jana
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The occurrence of food hypersensitivity reactions and the relation to the sensitization to grass and trees in atopic dermatitis patients 14 years of age and older

Indian Journal of Dermatology, 2019
Background: Although epidemiologic data are scarce, there is no doubt that the increase in pollen allergies is going to be followed by an increase in the so-called pollen-related food allergies.
Jarmila Celakovská, Josef Bukac, Karel Ettler, Jaroslava Vaneckova, Irena Krcmova, Kvetuse Ettlerova, Jan Krejsek   +6 more
doaj   +1 more source

Cross-Coupling Reactions of 5-Bromo-1,2,3-triazines [PDF]

, 2022
Lukas V. Hoff, Joana M. Hauser, Karl Gademann   +2 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Copper-Catalyzed Enantioconvergent Radical C(sp3)–N Cross-Coupling to Access Chiral α‑Amino-β-lactams

Precision Chemistry, 2023
Jing-Jing Zheng, Wei-Long Liu, Qiang-Shuai Gu, Zhong-Liang Li, Ji-Jun Chen, Xin-Yuan Liu   +5 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Synthesis of fluoroalkenes and fluoroenynes via cross-coupling reactions using novel multihalogenated vinyl ethers

Beilstein Journal of Organic Chemistry
In this study, we develop the synthesis methods of fluoroalkenes and fluoroenynes via Suzuki–Miyaura and Sonogashira cross-coupling reactions using novel multihalogenated fluorovinyl ethers, which are easily prepared from the reaction between phenols and
Yukiko Karuo, Keita Hirata, Atsushi Tarui, Kazuyuki Sato, Kentaro Kawai, Masaaki Omote   +5 more
doaj   +1 more source

Total and partial photoneutron reactions cross sections – new analysis and evaluation

EPJ Web of Conferences, 2012
The well-known problems of significant disagreements between partial photoneutron reactions (γ,n), (γ,2n) and (γ,3n) cross sections data obtained in various experiments are discussed.
Varlamov V.V., Ishkhanov B.S., Orlin V.N.   +2 more
doaj   +1 more source

Recent Advances in Noble Metal Nanocatalysts for Suzuki and Heck Cross-Coupling Reactions

Molecules, 2010
Since metal nanoparticles have a high surface-to-volume ratio and very active surface atoms, they are very attractive catalysts for a wide variety of organic and inorganic reactions, compared to bulk catalysts.
Radha Narayanan
doaj   +1 more source