Results 101 to 110 of about 3,415,769 (265)

Balanced Cross Sections and Retrodeformation [PDF]

In this exercise, students investigate the use of balanced cross sections and retrodeformation to study faults that do not break the surface and their application to tectonics, folding, and earthquake hazards.
Nicholas Pinter
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Progress on Neutron-Target Multipoles above 1 GeV

, 2012
We report a new extraction of nucleon resonance couplings using pi- photoproduction cross sections on the neutron. The world database for the process gn-->pi-p above 1 GeV has quadrupled with the addition of new differential cross sections from the CEBAF
A. Wrońska, A.E. Kudryavtsev, C. Guaraldo, D. Dutta, H. Gao, H. Ströher, I.I. Strakovsky, M. Mirazite, M. Paris, P. Rossi, R. Skibiński, R.L. Workman, S. Stepanyan, St. Kistryn, V.E. Tarasov, W. Chen, W.J. Briscoe   +16 more
core   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Extension of the Discrete Electron Transport Capabilities of the Geant4-DNA Toolkit to MeV Energies

Applied Sciences
The discrete physics models available in the Geant4-DNA Monte Carlo toolkit are a subject of continuous evolution and improvement in order to meet the needs of state-of-the-art radiobiological research for medical and space applications.
Ioanna Kyriakou, Hoang N. Tran, Laurent Desorgher, Vladimir Ivantchenko, Susanna Guatelli, Giovanni Santin, Petteri Nieminen, Sebastien Incerti, Dimitris Emfietzoglou   +8 more
doaj   +1 more source

SUSY Production Cross Sections [PDF]

, 1999
We summarize the status of next-to-leading order perturbative quantum chromodynamics (pQCD) calculations of the cross sections for the production of squarks, gluinos, neutralinos, charginos, and sleptons as a function of the produced sparticle masses in ...
Berger, Edmond L., Harris, Brian, Klasen, Michael, Tait, Tim   +3 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Determining of Cross Sections for 16O(n,α)13C reaction from Cross Sections of 13C(α,n)16O for the ground state

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
  In this study, light elements for 13C , 16O for  (α,n) and (n,α) reactions as well as α-particle energy  from 2.7 MeV  to 3.08 MeV are used as far as the data of reaction cross sections are available.
Sameera A. Ebrahiem, Maher N. Sarsam, Hermez M. Youhana, Nebras T. Abd-Al-Hameed   +3 more
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source