Results 71 to 80 of about 88,289 (319)
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang +12 more
wiley +1 more source
Serial Correlations of Partial Body Weight and Feed Intake in Crossbred Cattle
Feeding behavior in cattle affects feed efficiency, which is important for increasing the profitability of production while simultaneously reducing the environmental impact.
Georgette Pyoos +4 more
doaj +1 more source
Heat stress is an important issue in the global dairy industry. In tropical areas, an alternative to overcome heat stress is the use of crossbred animals or synthetic breeds, such as the Girolando.
P. I. Otto +15 more
semanticscholar +1 more source
The SIRT5/ACAA2 axis maintains lipid metabolic homeostasis in RTECs by promoting ACAA2 desuccinylation and preserving its stability and enzymatic activity, thereby sustaining FAO and limiting PUFA and PUFA‐containing phospholipid accumulation. Under CaOx stress, SIRT5 downregulation impairs FAO, promotes oxidative stress and ferroptosis, and enhances ...
Qinhong Jiang +6 more
wiley +1 more source
Evaluation of the Growth Rates and Biometric Traits in Meat Crossbred Calves
The aim of this study was to evaluate the body weight and some biometric measurements on meat crossbred calves comparative with Romanian Black Spotted dairy calves at weaning (4 months).
Marinela Enculescu +2 more
doaj
Para se avaliar o desempenho (ganho de peso e conversão alimentar), o consumo de nutrientes e a digestibilidade aparente de vários nutrientes, foram utilizados 36 garrotes inteiros, 12 Nelore, 12 ½ sangue Holandês-Nelore e 12 ½ sangue ...
Henrique Jorge Fernandes +6 more
doaj +1 more source
Chromosomal instability of purebred and crossbred dairy cows
The article presents the results of research on the karyotype characteristics variability in purebred and crossbred dairy cows. The material for the research was peripheral blood samples of purebred firstborn cows of the Ukrainian red-spotted dairy and ...
V. Dzitsiuk, L. Starodub, T. Dyman
core +1 more source
The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi +6 more
wiley +1 more source
Three generations of crossbred cows from a 3-breed rotation of the Viking Red (VR), Montbéliarde (MO), and Holstein (HO) breeds were compared with HO herdmates in 7 high-performance, commercial dairy herds in Minnesota.
A. Hazel, B. Heins, L. Hansen
semanticscholar +1 more source
Drug Repurposing for Treating NCOR‐Related Intellectual Disability
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong +15 more
wiley +1 more source

