Results 131 to 140 of about 30,451 (371)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Thermal comfort indexes and physiological parameters of Santa Inês and crossbreed ewes in the semi-arid

open access: yes, 2017
The objective of this study was evaluated the thermal comfort indexes and physiological parameters in Santa Ines and crossbreed ewes in Brazilian semiarid.
D. A. Furtado   +5 more
semanticscholar   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

BAYES' ESTIMATES OF THE DOUBLE HURDLE MODEL IN THE PRESENCE OF FIXED COSTS [PDF]

open access: yes
We present a model of market adoption (participation) where the presence of non-negligible fixed costs leads to non-zero censoring of the traditional double-hurdle regression.
Barrett, Christopher B.   +2 more
core   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Dairy cattle management: survey on dairy cattle lactation trend in Sabah [PDF]

open access: yes
A survey was conducted to obtain information on Sabah dairy cattle lactation length and lactation yield to identify the lactation trend. In the study, 18 farms with 2 types of husbandry practice namely feedlot and grazing were visited.
Ahmad, Abdul Hamid   +2 more
core   +1 more source

Milk Production, Physiological Condition and Performance of Etawa Crossbreed Goats Feed by Ration Supplemented with Mangosteen Peel Flour

open access: yes, 2018
Study on the effect of the addition of mangosteen (Garcinia mangostana L.) peel flour on physiological condition and performance of Etawa crossbreed goats was done.
Dzarnisa   +4 more
semanticscholar   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Perbandingan Nilai Mppa Produksi Susu antara Sapi Perah Friesian Holstein dan Peranakan Friesian Holstein di Balai Besar Pembibitan Ternak Unggul dan Hijauan Pakan Ternak Baturraden Purwokerto [PDF]

open access: yes, 2015
Value Most Probable Producing Ability (MPPA) is a maximum estimate of the ability an animal to produce females that counts or is suspected on the basis of the performance records exist.
Aditya, F. (Febi)   +2 more
core  

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