A neuroimmune-enriched multibiofluid proteomic index associated with cognitive-motor progression in early Parkinson's disease: a longitudinal PPMI cohort study. [PDF]
Wang H +6 more
europepmc +1 more source
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab +19 more
wiley +1 more source
An integrated bioinformatics analysis identifying ALOX15 as a novel pharmacological target for retinitis pigmentosa and diabetic retinopathy. [PDF]
Yan W, He Q, Zhang L, Wang H.
europepmc +1 more source
Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study
ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl +6 more
wiley +1 more source
Crossed Modules of Inverse Semigroups as Internal Categories
A classical result of Spencer and Brown (1976) shows that the category of crossed modules of groups is equivalent to the category of 2-groups. We extend this equivalence to inverse semigroups.
Zeidler, David
core +1 more source
Commentary: Epitranscriptomic regulation by m6A in immunity and autoimmune disorders: emerging mechanisms and clinical perspectives. [PDF]
Zhang S, Li T, Liu Y.
europepmc +1 more source
Computing exterior isoclinism of crossed modules
In this paper, we introduce exterior isoclinism for crossed modules, extending the concept of isoclinism from groups to these 2-dimensional algebraic structures.
ODABAŞ, Alper, ARVASİ, Zekeriya
core +1 more source
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai +13 more
wiley +1 more source
Dissecting the cell biology of the ISR in cognitive disorders at the single-cell resolution. [PDF]
Kaang BK.
europepmc +1 more source
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks +8 more
wiley +1 more source

