Results 151 to 160 of about 122,193 (311)

Additive genetic variance and covariance between relatives in wheat crosses with variable parental ploidy levels

, 2020
Synthetic hexaploid wheat was developed and used in breeding to introduce new genetic diversity into bread wheat, through interspecific hybridization of T. tauschii (diploid) and durum wheat T.
Puhl, Laura E, Crossa, Jose, Cantet, R. J. C., Sebastian, Munilla, Pérez-Rodríguez, Paulino   +4 more
core  

Identification of promising wheat genotypes for crossing

Crop Breeding and Applied Biotechnology, 2011
The objective of this study was to identify promising wheat genotypes from the IAPAR breeding program for crosses by multivariate techniques. Measures of dissimilarity between genotypes were obtained from multicategoric variables.
Luciana Costa, Carlos Roberto Riede, Claudemir Zucareli, Valéria Carpentieri Pípolo, Deoclécio Domingos Garbuglio   +4 more
doaj  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Cross-border preimplantation genetic diagnosis

Reproductive Biomedicine & Society Online, 2018
Couture, Vincent, Drouin, Régen, Moutquin, Jean-Marie, Bouffard, Chantal   +3 more
openaire   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Genetic parameters for egg production traits in crosses between local and exotic chickens estimated by Bayesian inference

, 2020
Estimates of genetic parameters for economic traits are important to enable the breeder estimate the breeding value of individuals available for selection.
Udeh, I., Omeje, S.I.
core  

MICROSATELLITE DIVERSITY OF CROSSBRED HORSES RAISED IN BOSNIA AND HERZEGOVINA

Genetics & Applications, 2017
The focus of this study was microsatellite diversity of crossbred horses raised in Bosnia and Herzegovina. Genomic DNA was extracted from blood samples of 20 individuals (KBA group – 7 individuals, crosses between Bosnian and Herzegovinian mountain ...
Dunja Rukavina, Danica Hasanbašić, Belma Kalamujić Stroil, Naris Pojskić   +3 more
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The efficiency of selection in the early generations of a potato breeding programme

, 2015
The efficiency of selection in the early generations of a potato breeding programme is examined. A number of unselected potato (Solanum tuberosum L) clones were grown in a glasshouse, from true botanical seed, and thereafter in the field at two ...
Brown, Jack
core