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Dissecting genetic correlation and pleiotropy through a genetic cross

2023
AbstractGenetic correlation represents an important class of evolutionary constraint, which is itself evolvable. Empirical studies have found mixed results on whether genetic correlations change rapidly or slowly. This uncertainty challenges our ability to predict the outcome of selection.
Haoran Cai   +2 more
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Genetically Encoded Cleavable Protein Photo-Cross-Linker

Journal of the American Chemical Society, 2014
We have developed a genetically encoded, selenium-based cleavable photo-cross-linker that allows for the separation of bait and prey proteins after protein photo-cross-linking. We have further demonstrated the efficient capture of the in situ generated selenenic acid on the cleaved prey proteins. Our strategy involves tagging the selenenic acid with an
Shixian, Lin   +5 more
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Genetics of interracial crosses in Hawaii

Eugenics Quarterly, 1962
(1962). Genetics of interracial crosses in Hawaii. Eugenics Quarterly: Vol. 9, No. 1, pp. 23-24.
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Population genetics of unequal crossing over

Journal of Molecular Evolution, 1975
The population genetics of unequal crossing over was examined for an infinite population with random mating. The following cases were considered: 1. There is an initial portion of duplicated genes which offer the opportunity for unequal crossing over, but the primary event leading to the duplication does not occur any more (model 1a). 2.
J. Krüger, F. Vogel
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Cross Dock Scheduling Using Genetic Algorithms

2007 International Symposium on Computational Intelligence in Robotics and Automation, 2007
Cross docking is a distribution system in which the merchandise received at a warehouse or distribution center is not stocked but immediately prepared for onward shipment. In other words, cross docking is the transfer of inward deliveries from the point of reception directly to the point of delivery with limited or no interim storage. One way to reduce
Shayla Ley, Sherif Elfayoumy
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Genetic Map Location of Afr-1: Results From Four Genetic Crosses

1988
Afr-1 is a genetic locus in mice that controls the adult level of serum alpha-fetoprotein. Under normal circumstances, AFP synthesis is repressed shortly after birth, from levels approaching 10 million nanograms/milliliter to adult levels of only several hundred ng/ml (Olsson et al., 1977) .
E P, Blankenhorn   +3 more
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Genetic analysis of the mouse using interspecific crosses

Trends in Genetics, 1988
Abstract Interspecific mouse crosses used in conjunction with cloned sequences are facilitating gene localization and high resolution meiotic analysis of the mouse genome. Determination of the recombination breakpoints on individual chromosomes allows gene ordering by ‘pedigree analysis' rather than by recombination distance estimation alone.
P, Avner   +3 more
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Genetically encoded selective cross-linkers and emerging applications

Biochemical Society Transactions, 2020
There has been a large amount of interest in the development of genetically encoded cross-linkers that target functional groups naturally present in cells. Recently, a new class of unnatural amino acids that specifically react with target residues were developed and genetically incorporated. The selective reaction shows higher cross-linking efficiency,
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Population genetic aspects of cross-fertilization

1995
A model that is often used to derive the population genetic implications of cross-fertilization is that of the panmictic population. For such a population one assumes: 1. random mating; 2. absence of random variation of allele frequencies; 3. absence of selection; 4. absence of mutation; 5. absence
Izak Bos, Peter Caligari
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The genetic detection of natural crossing in blackberry

Genetica, 1955
1. The pollination system in 4x blackberry was studied from vicinism (cross-pollination with neighbouring plants) in a row of Merton Thornless plants situated between rows of thornyRubus, using glandularv. eglandular cotyledons as markers. 2. Average hybridization was 17%, ranging from 5 to 32% in different flower samples.
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