Results 51 to 60 of about 7,900,479 (301)

Genetic draft and valley crossing [PDF]

, 2018
ABSTRACT Living systems are characterized by complex adaptations which require multiple coordinated mutations in order to function. Empirical studies of fitness landscapes that result from the many possible mutations in a gene region reveal many fitness peaks and valleys that connect them.
Kessinger, Taylor, Van Cleve, Jeremy
openaire   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice

Communications Biology, 2021
Button-Simons et al. report on two different genetic crosses of Plasmodium falciparum derived from Asian and African origin parasites, and generate large numbers of recombinant progeny.
Katrina A. Button-Simons, Sudhir Kumar, Nelly Carmago, Meseret T. Haile, Catherine Jett, Lisa A. Checkley, Spencer Y. Kennedy, Richard S. Pinapati, Douglas A. Shoue, Marina McDew-White, Xue Li, François H. Nosten, Stefan H. Kappe, Timothy J. C. Anderson, Jeanne Romero-Severson, Michael T. Ferdig, Scott J. Emrich, Ashley M. Vaughan, Ian H. Cheeseman   +18 more
doaj   +1 more source

Study on the Effect of Mass Selection and Hybridization on Growth Performance of Chinese Pearl Oyster Pinctada martensii

Frontiers in Marine Science, 2022
The pearl oyster Pinctada martensii is an important species for sea pearl production in China. To explore the influence of the combination of mass selection and hybridization on growth performance of P.
Chao Fan, Xuekai Zhang, Liming Tang, Xingzhi Zhang, Jinlong Li, Yangchun Li, Qiongzhen Li, Zhaoping Wang   +7 more
doaj   +1 more source

Genetic diversity and population structure of sugarcane (Saccharum spp.) accessions by means of microsatellites markers

Acta Scientiarum. Agronomy, 2020
The success of sugarcane (Saccharum spp.) breeding programs depends on the choice of productive parent lines that have a high industrial yield and are genetically divergent. This study assessed the genetic divergence and population structure of sugarcane
Hugo Zeni Neto, Luiz Gustavo da Mata Borsuk, Luiz Renato Frederico dos Santos, Henrique Sanches Angeli, Guilherme Souza Berton, Lorena Lopes de Sousa   +5 more
doaj   +1 more source

Supporting long‐term sustainability of ex situ collections using a pedigree‐based population management approach

Applications in Plant Sciences, 2022
Premise Living collections maintained for generations are at risk of diversity loss, inbreeding, and adaptation to cultivation. To address these concerns, the zoo community uses pedigrees to track individuals and implement crosses that maximize founder ...
Jeremy A. Foster, Seana K. Walsh, Kayri Havens, Andrea T. Kramer, Jeremie B. Fant   +4 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Pre-breeding in sugarcane (Saccharum sp. hybrids) for red rot resistance and economic traits [PDF]

Electronic Journal of Plant Breeding, 2010
The present investigation is concerned with the development of genetic stocks for resistance to red rot disease caused byColletotrichum falcatum Went and other important economic traits.
C. Babu
doaj