Results 61 to 70 of about 2,124,367 (296)
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
The objective of the present study was to evaluate 44 soybean octuple crosses in the F4:3[8] and F5:3[8] generations in order to select progenies superior for seed oil yield (OY) and other important agronomic characteristics.
Hamawaki Osvaldo Toshiyuki +2 more
doaj
Genetic analysis in the Collaborative Cross breeding population [PDF]
Genetic reference populations in model organisms are critical resources for systems genetic analysis of disease related phenotypes. The breeding history of these inbred panels may influence detectable allelic and phenotypic diversity. The existing panel of common inbred strains reflects historical selection biases, and existing recombinant inbred ...
Philip, Vivek M +24 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Molecular parentage analysis is essential in breeding Asian seabass.
In aquaculture species, maintaining pedigree information and genetic variation in each generation is essential, but very difficult. In this study, we used nine microsatellites to genotype 2,520 offspring from four independent full-factorial crosses (10 ...
Peng Liu +7 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
DesignGG: an R-package and web tool for the optimal design of genetical genomics experiments [PDF]
BACKGROUND: High-dimensional biomolecular profiling of genetically different individuals in one or more environmental conditions is an increasingly popular strategy for exploring the functioning of complex biological systems.
Fu, Jingyuan; id_orcid +32 more
core +2 more sources
Editorial: Cross-disorder Genetics in Neuropsychiatry [PDF]
Evelien Van Assche +8 more
openaire +4 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
INTERFERENCE IN GENETIC CROSSING OVER AND CHROMOSOME MAPPING
ABSTRACT This paper proposes a general model for interference in genetic crossing over. The model assumes serial Occurrence of chiasmata, visualized as a renewal process along the paired (or pairing) chromosomes. This process is described as an underlying Poisson process in which the Ist, n + 1th, 2n + 1th, etc., events are to be ...
openaire +3 more sources

