Results 61 to 70 of about 122,193 (311)

Overview of genetic crosses to generate SB|Trp53|Onc3 mouse model.

open access: yes, 2021
Schematic of genetic crosses to generate the genetic cohorts aged for tumor development in this study. (TIFF)
Amanda L. Meshey (11278937)   +20 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Genetic variation and quantitative trait loci associated with developmental stability and the environmental correlation between traits in maize

open access: yes, 2008
There is limited experimental information about the genetic basis of micro-environmental variance (V-E) (developmental stability) and environmental correlations.
Hill, William G.   +4 more
core   +1 more source

Genetic control of incubation behavior in the domestic hen [Генетический контроль поведения при насиживании яиц у домашних кур. (Великобритания)] [PDF]

open access: yes, 2002
The genetic control of incubation behavior was investigated in the domestic hen by analysis of the incidence of the behavior in reciprocal crosses between nonbroody White Leghorn (WL) and broody Bantam (B) lines and in a backcross of F1 males (WL male x ...
Talbot, Richard   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Pre-breeding in sugarcane (Saccharum sp. hybrids) for red rot resistance and economic traits [PDF]

open access: yesElectronic Journal of Plant Breeding, 2010
The present investigation is concerned with the development of genetic stocks for resistance to red rot disease caused byColletotrichum falcatum Went and other important economic traits.
C. Babu
doaj  

The system of genetic exchange in Trypanosoma brucei and other trypanosomatids [PDF]

open access: yes, 2007
In this chapter, we discuss our current understanding of the systems of genetic exchange in trypanosomatids and the im-pact the recent genome projects have had on this area of research.
Turner, C.M.R., Tait, A., MacLeod, A.
core  

Usefulness Criterion and Post-selection Parental Contributions in Multi-parental Crosses: Application to Polygenic Trait Introgression

open access: yesG3: Genes, Genomes, Genetics, 2019
Predicting the usefulness of crosses in terms of expected genetic gain and genetic diversity is of interest to secure performance in the progeny and to maintain long-term genetic gain in plant breeding.
Antoine Allier   +4 more
doaj   +1 more source

Cross-border genetic testing [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2010
As genetic testing (GT) is now available for many rare disorders, no GT laboratory can be expert enough to provide every test. Samples are therefore sent between laboratories for testing, often across borders. Such cross-border testing raises some questions: The 2003 OECD survey of 827 molecular GT laboratories in 18 countries found that 64% of ...
openaire   +2 more sources

Efficient Synthesis of Mutants Using Genetic Crosses [PDF]

open access: yesProceedings of the 2018 ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics, 2018
Abstract The genetic cross is a fundamental, flexible, and widely-used experimental technique to create new mutant strains from existing ones. Surprisingly, the problem of how to efficiently compute a sequence of crosses that can make a desired target mutant from a set of source mutants has received scarce attention.
Aditya Pratapa   +3 more
openaire   +2 more sources

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