Results 91 to 100 of about 9,924,168 (281)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
On the Crossing Numbers of Cartesian Products of Stars and Graphs of Order Six
Discussiones Mathematicae Graph Theory, 2013 The crossing number cr(G) of a graph G is the minimal number of crossings over all drawings of G in the plane. According to their special structure, the class of Cartesian products of two graphs is one of few graph classes for which some exact values of ...
Klešč Marián, Schrötter Štefan
doaj +1 more source
Correlation Between Executive Function and Walk While Crossing Over an Obstacle Under Different Gait Phases. [PDF]
Dement Neurocogn Disord, 2023 Lee SM, Lee HS.
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Do wild ungulates utilize at-grade fauna passages as effectively as fauna overpasses or underpasses?
Frontiers in Conservation ScienceAt-grade fauna passages are much less resources demanding to construct compared to wildlife overpasses or underpasses at infrastructure barriers. Because smaller and intermediate-sized roads are much more common than major roads in most landscapes, at ...
Marcus Elfström, Mattias Olsson
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Kick it over - No. 33 (Spring 1994)
, 1994 A social anarchist and anti-authoritarian quarterly publication. In this issue: "Women and anarchism" - Do anarchists tolerate sexual harassment?, Power feminism, Grandview Girl's ...
core +1 more source