Results 91 to 100 of about 308,108 (272)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Ecology and EvolutionA balanced lethal system is a genetic disease that results in the loss of half of the reproductive output. The best‐known balanced lethal system is found in newts of the genus Triturus. In these newts, two different versions of chromosome 1, named 1A and
Willem R. M. Meilink +7 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Genetics and Molecular Biology, 2003 Ethidium bromide (EB) is an intercalating inhibitor of topoisomerase II and its activities are related to chemotherapeutic drugs used in anti-cancer treatments. EB promotes several genotoxic effects in exposed cells by stabilising the DNA-enzyme complex.
Tânia C.A. Becker +3 more
doaj +1 more source
Observing random walks of atoms in buffer gas through resonant light absorption
, 2016 Using resonant light absorption, random walk motions of rubidium atoms in nitrogen buffer gas are observed directly. The transmitted light intensity through atomic vapor is measured and its spectrum is obtained, down to orders of magnitude below the shot
Aoki, Kenichiro, Mitsui, Takahisa
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Insect pollinator crossing of international border barriers along the U.S.-Mexico border
Ecological IndicatorsInfrastructure along the U.S.-Mexico Border may not be equally permeable to all types of insect pollinators with potential implications for pollen and gene flow between plant populations. Pollinators were observed on their approach to two types of border
Beth A. Middleton
doaj +1 more source
Violation of Bohr's Complementarity: One Slit or Both?
, 2006 We have implemented a novel double-slit "which-way" experiment which raises interesting questions of interpretation. Coherent laser light is passed through a converging lens and then through a dual pinhole producing two beams crossing over at the focal ...
Afshar, Shahriar S.
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
International Journal of Infectious DiseasesIntroduction: To contribute to health of Palestine refugees displaced by the Israel–Hamas War of 2023, we examined changes in shipment of relief supplies for the Palestine refugees displaced by the Israel–Hamas War of 2023 donated by the United Nations ...
Dr Soichi Takeishi
doaj +1 more source