Results 71 to 80 of about 1,682,758 (272)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Safety Risk Assessment of Double-Line Tunnel Crossings Beneath Existing Tunnels in Complex Strata

open access: yesBuildings
With the acceleration of urbanization, the development of urban rail transit networks has become an essential component of modern urban transportation.
Bafeng Ren   +4 more
doaj   +1 more source

Appreciation of Special Combinative Capacity at Three Oryctolagus Cunicullus Populations from Timis County, for Average Nest Weight and Corporal Mass of the Descendants at the Age of 7 Days

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Non additive genetic component that is the base of a quantitative character has no predictability, this is the reason for which the present paper is proposing to appreciate the special combinatory capacity for corporal mass of the descendants at birth in
Dorel Dronca   +8 more
doaj  

The Orchard crossing number of an abstract graph

open access: yes, 2009
We introduce the Orchard crossing number, which is defined in a similar way to the well-known rectilinear crossing number. We compute the Orchard crossing number for some simple families of graphs. We also prove some properties of this crossing number.
Abstract Graph, David Garber, Elie Feder
core   +2 more sources

Agreeing to Cross: How Drivers and Pedestrians Communicate

open access: yes, 2017
The contribution of this paper is twofold. The first is a novel dataset for studying behaviors of traffic participants while crossing. Our dataset contains more than 650 samples of pedestrian behaviors in various street configurations and weather ...
Kotseruba, Iuliia   +2 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Genotype × Environment Interaction and Correlations Between Agronomic Traits, Flowering, and Fruit Set in Cassava

open access: yesHorticulturae
The lack of synchronization and low flowering rates in cassava (Manihot esculenta Crantz) present significant challenges for breeding programs.
Luana da Silva Guedes   +2 more
doaj   +1 more source

Curve Crossing Problems: Analytically solvable model

open access: yes, 2004
We propose an exactly solvable model for the two state curve crossing problems. Our model assumes the coupling to be a delta function. It is used to calculate the effect of curve crossing on electronic absorption spectrum and resonance Raman excitation ...
Chakraborty, Aniruddha
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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