Results 271 to 280 of about 1,321,651 (326)

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Bridging priorities: Stakeholder preferences, networks, and barriers in road-stream crossing management. [PDF]

PLoS One
Asadifakhr K, Huang J, Perkins P, Lucey K, Wang H, Han F, Mo W.   +6 more
europepmc   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

FRAP-CROSS technique: Fracking and Rendezvous-PIERCE for intracalcium crossing in femoropopliteal diffuse calcified occlusions. [PDF]

CVIR Endovasc
Haraguchi T, Tsujimoto M, Leung RW, Chang Y, Kasai Y, Hachinohe D, Kashima Y.   +6 more
europepmc   +1 more source

Crossing the Numbers Barrier [PDF]

, 2010
Allen, C., Boyce, Paul
openaire  

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Migratory connectivity and barrier-crossing flights of Vermivora warblers are associated with synoptic weather conditions. [PDF]

J Anim Ecol
Kramer GR, Andersen DE, Buehler DA, Wood PB, Peterson SM, Lehman JA, Aldinger KR, Bulluck LP, Harding SR, Jones JA, Loegering JP, Smalling C, Vallender R, Streby HM.   +13 more
europepmc   +1 more source

Tunable Octdong and Spindle-Torus Fermi Surfaces in Kramers Nodal Line Metals. [PDF]

Nat Commun
Domaine G, Hirschmann MM, Parshukov K, Date M, Meyerheim HL, Watson MD, Mohseni K, Dufresne SKY, Terakawa S, Rosmus M, Olszowska N, Parkin SSP, Schnyder AP, Schröter NBM.   +13 more
europepmc   +1 more source