Results 81 to 90 of about 10,813,555 (336)

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

On the Rectilinear Crossing Number of Complete Uniform Hypergraphs

open access: yes, 2016
In this paper, we consider a generalized version of the rectilinear crossing number problem of drawing complete graphs on a plane. The minimum number of crossing pairs of hyperedges in the $d$-dimensional rectilinear drawing of a $d$-uniform hypergraph ...
Anshu, Anurag   +3 more
core   +1 more source

Triple Crossing Number of Knots and Links [PDF]

open access: yes, 2012
A triple crossing is a crossing in a projection of a knot or link that has three strands of the knot passing straight through it. A triple crossing projection is a projection such that all of the crossings are triple crossings.
C. Adams
semanticscholar   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

The crossing number of locally twisted cubes [PDF]

open access: yes, 2011
The {\it crossing number} of a graph $G$ is the minimum number of pairwise intersections of edges in a drawing of $G$. Motivated by the recent work [Faria, L., Figueiredo, C.M.H.
Liu, Bao   +5 more
core  

Selection strategies for the development of maize introgression populations. [PDF]

open access: yesPLoS ONE, 2014
Introgression libraries are valuable resources for QTL detection and breeding, but their development is costly and time-consuming. Selection strategies for the development of introgression populations with a limited number of individuals and high ...
Eva Herzog   +5 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Counting and Enumerating Crossing-free Geometric Graphs

open access: yes, 2016
We describe a framework for counting and enumerating various types of crossing-free geometric graphs on a planar point set. The framework generalizes ideas of Alvarez and Seidel, who used them to count triangulations in time $O(2^nn^2)$ where $n$ is the ...
Wettstein, Manuel
core   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Crossing Minimization for 1-page and 2-page Drawings of Graphs with Bounded Treewidth

open access: yes, 2014
We investigate crossing minimization for 1-page and 2-page book drawings. We show that computing the 1-page crossing number is fixed-parameter tractable with respect to the number of crossings, that testing 2-page planarity is fixed-parameter tractable ...
Bannister, Michael J., Eppstein, David
core   +1 more source

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