Results 71 to 80 of about 307,259 (304)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Crossing Numbers of Periodic Graphs [PDF]

open access: yesJournal of Graph Theory, 2015
AbstractA graph is periodic if it can be obtained by joining identical pieces in a cyclic fashion. It is shown that the limit crossing number of a periodic graph is computable. This answers a question of Richter [1, Problem 4.2].
Zdenek Dvorák 0001, Bojan Mohar
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Crossing Number of the Cone of a Graph [PDF]

open access: yesSIAM Journal on Discrete Mathematics, 2016
Motivated by a problem asked by Richter and by the long standing Harary-Hill conjecture, we study the relation between the crossing number of a graph $G$ and the crossing number of its cone $CG$, the graph obtained from $G$ by adding a new vertex adjacent to all the vertices in $G$.
Carlos A. Alfaro   +3 more
openaire   +2 more sources

Selection strategies for the development of maize introgression populations. [PDF]

open access: yesPLoS ONE, 2014
Introgression libraries are valuable resources for QTL detection and breeding, but their development is costly and time-consuming. Selection strategies for the development of introgression populations with a limited number of individuals and high ...
Eva Herzog   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Conjectures About Wheels Without One Edge with Paths and Cycles

open access: yesMathematics
The crossing number cr(G) of a graph G is the minimum number of edge crossings over all drawings of G in the plane. The main aim of this paper is to give the crossing numbers of the join products G*+Pn and G*+Cn for the connected graph G* obtained by ...
Michal Staš, Mária Timková
doaj   +1 more source

A Note on the Crossing Numbers of 5-Regular Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2020
The crossing number cr(G) of a graph G is the smallest number of edge crossings in any drawing of G. In this paper, we prove that there exists a unique 5-regular graph G on 10 vertices with cr(G) = 2.
Ouyang Zhangdong
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A Comparison of Void-finding Algorithms Using Crossing Numbers

open access: yesThe Astrophysical Journal, 2023
We study how well void-finding algorithms identify cosmic void regions and whether we can quantitatively and qualitatively compare the voids they find with dynamical information from the underlying matter distribution.
Dahlia Veyrat   +2 more
doaj   +1 more source

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